The current status of mesenchymal stromal cells: controversies, unresolved issues and some promising solutions to improve their therapeutic efficacy

D García-Bernal, M García-Arranz… - Frontiers in Cell and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in
advanced therapies with different purposes, most of which are related with inflammatory …

Antimicrobial activity of mesenchymal stem cells: current status and new perspectives of antimicrobial peptide-based therapies

F Alcayaga-Miranda, J Cuenca, M Khoury - Frontiers in immunology, 2017 - frontiersin.org
While mesenchymal stem cells (MSCs)-based therapy appears to be promising, there are
concerns regarding possible side effects related to the unwanted suppression of …

Endometrial and menstrual blood mesenchymal stem/stromal cells: biological properties and clinical application

M Bozorgmehr, S Gurung, S Darzi, S Nikoo… - Frontiers in cell and …, 2020 - frontiersin.org
A highly proliferative mesenchymal stem/stromal cell (MSC) population was recently
discovered in the dynamic, cyclically regenerating human endometrium as clonogenic …

MSCs and inflammatory cells crosstalk in regenerative medicine: concerted actions for optimized resolution driven by energy metabolism

V Planat-Benard, A Varin, L Casteilla - Frontiers in immunology, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are currently widely used in cell based therapy
regarding to their remarkable efficacy in controlling the inflammatory status in patients …

Molecular and cellular pathogenesis of endometriosis

PAB Klemmt, A Starzinski-Powitz - Current women's health …, 2018 - ingentaconnect.com
Background: A substantial body of studies supports the view that molecular and cellular
features of endometriotic lesions differ from those of eutopic endometrium. Apart from that …

Autologous menstrual blood-derived stromal cells transplantation for severe Asherman's syndrome

J Tan, P Li, Q Wang, Y Li, X Li, D Zhao… - Human …, 2016 - academic.oup.com
STUDY QUESTION Does autologous transplantation of menstrual blood-derived stromal
cells (menSCs) regenerate endometrium to support pregnancy in patients with severe …

Mesenchymal stem cell therapy for acute respiratory distress syndrome: from basic to clinics

H Qin, A Zhao - Protein & cell, 2020 - academic.oup.com
The 2019 novel coronavirus disease (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has occurred in China and around the world. SARS …

Mesenchymal stromal cells anno 2019: dawn of the therapeutic era? Concise review

MJ Hoogduijn, E Lombardo - Stem cells translational medicine, 2019 - academic.oup.com
Summary 2018 was the year of the first marketing authorization of an allogeneic stem cell
therapy by the European Medicines Agency. The authorization concerns the use of …

Antibacterial activity of human mesenchymal stem cells mediated directly by constitutively secreted factors and indirectly by activation of innate immune effector cells

L Chow, V Johnson, R Impastato, J Coy… - Stem cells …, 2020 - academic.oup.com
Mesenchymal stem cells (MSC) have been shown to improve wound healing and suppress
inflammatory immune responses. Newer research also indicates that MSC exhibit …

SARS-CoV-2 infection and lung regeneration

F Zhao, Q Ma, Q Yue, H Chen - Clinical Microbiology Reviews, 2022 - Am Soc Microbiol
The lung is the primary site of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2)-induced immunopathology whereby the virus enters the host cells by binding to …