Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell–cell communication by chemokines

S Gyoneva, RM Ransohoff - Trends in pharmacological sciences, 2015 - cell.com
Traumatic brain injury (TBI) affects millions of people worldwide every year. The primary
impact initiates the secretion of pro-and anti-inflammatory factors, subsequent recruitment of …

Current understanding of neuroinflammation after traumatic brain injury and cell-based therapeutic opportunities

Y Xiong, A Mahmood, M Chopp - Chinese Journal of Traumatology, 2018 - mednexus.org
Traumatic brain injury (TBI) remains a major cause of death and disability worldwide.
Increasing evidence indicates that TBI is an important risk factor for neurodegenerative …

Neural stem cell therapy for subacute and chronic ischemic stroke

AC Boese, QSE Le, D Pham, MH Hamblin… - Stem cell research & …, 2018 - Springer
Neural stem cells (NSCs) play vital roles in brain homeostasis and exhibit a broad repertoire
of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a …

Stromal cell-derived factor-1 (SDF-1): homing factor for engineered regenerative medicine

TT Lau, DA Wang - Expert opinion on biological therapy, 2011 - Taylor & Francis
Introduction: Stromal cell-derived factor-1α (SDF-1) is a chemokine that plays a major role in
cell trafficking and homing of CD34+ stem cells. Studies employing SDF-1/CXCR4 have …

Neurogenesis in adult human brain after traumatic brain injury

WM Zheng, Q ZhuGe, M Zhong, G Chen, B Shao… - 2013 - liebertpub.com
While much work has been conducted regarding the neurogenesis response to traumatic
brain injury (TBI) in rodents, it remains largely unknown whether neurogenesis in adult …

Regulation of endogenous neural stem/progenitor cells for neural repair—factors that promote neurogenesis and gliogenesis in the normal and damaged brain

KJ Christie, AM Turnley - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Neural stem/precursor cells in the adult brain reside in the subventricular zone (SVZ) of the
lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus in the hippocampus …

[HTML][HTML] Neural stem cell therapy for neurovascular injury in Alzheimer's disease

AC Boese, MH Hamblin, JP Lee - Experimental neurology, 2020 - Elsevier
Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by
progressive neurodegeneration leading to severe cognitive decline and eventual death. AD …

Neural stem cells for early ischemic stroke

MH Hamblin, JP Lee - International journal of molecular sciences, 2021 - mdpi.com
Clinical treatments for ischemic stroke are limited. Neural stem cell (NSC) transplantation
can be a promising therapy. Clinically, ischemia and subsequent reperfusion lead to …

[HTML][HTML] Cortical lesion stimulates adult subventricular zone neural progenitor cell proliferation and migration to the site of injury

B Saha, S Peron, K Murray, M Jaber, A Gaillard - Stem cell research, 2013 - Elsevier
The subventricular zone (SVZ) is the principal neurogenic niche present in the adult non-
human mammalian brain. Neurons generated in the SVZ migrate along the rostral migratory …

Exosomes and nano-SDF scaffold as a cell-free-based treatment strategy improve traumatic brain injury mechanisms by decreasing oxidative stress …

M Hajinejad, MH Ebrahimzadeh… - Stem Cell Reviews and …, 2023 - Springer
Traumatic brain injury (TBI) causes a variety of complex pathological changes in brain
parenchymal tissue by increasing neuroinflammatory and apoptosis responses. Currently …