The biological basis of the neurodegenerative movement disorder, Parkinson's disease
(PD), is still unclear despite it being 'discovered'over 200 years ago in Western Medicine …

Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease (AD). It is characterized by a progressive loss of dopaminergic neurons …

Pathology of neurodegenerative diseases can be correlated with intra-neuronal as well as
extracellular changes which lead to neuronal degeneration. The central nervous system …

There is a pressing need for disease-modifying therapies in patients suffering from
neurodegenerative diseases, including Parkinson's disease (PD). However, these disorders …

Mapping gray matter (GM) pathology in Parkinson's disease (PD) with conventional MRI is
challenging, and the need for more sensitive brain imaging techniques is essential to …

Imaging biomarkers for immune activation may be valuable for early-stage detection,
therapeutic testing, and research on neurodegenerative conditions. In the present study, we …

Epidemiologically Parkinson's disease (PD) is associated with chronic ingestion or
inhalation of environmental toxins leading to the development of motor symptoms. Though …

Diffusion kurtosis imaging (DKI) is sensitive in detecting α-Synuclein (α-Syn) accumulation-
associated microstructural changes at late stages of the pathology in α-Syn overexpressing …

Background Diffusion kurtosis imaging has been applied to evaluate white matter and basal
ganglia microstructure in mixed Parkinson's disease (PD) groups with inconclusive results …

Clinical diagnosis of Parkinson's disease (PD) occurs typically when a substantial proportion
of dopaminergic neurons in the substantia nigra (SN) already died, and the first motor …