Cellular and molecular mechanisms regulating the KNDy neuronal activities to generate and modulate GnRH pulse in mammals
Accumulating findings during the past decades have demonstrated that the hypothalamic
arcuate kisspeptin neurons are supposed to be responsible for pulsatile release of …
arcuate kisspeptin neurons are supposed to be responsible for pulsatile release of …
Kisspeptin neurons as an integration center of reproductive regulation: observation of reproductive function based on a new concept of reproductive regulatory …
H Ozawa - Reproductive medicine and biology, 2022 - Wiley Online Library
Background Regulation of the reproductive system has been explained by the actions and
feedback of gonadotropin releasing hormone‐luteinizing hormone/follicle stimulating …
feedback of gonadotropin releasing hormone‐luteinizing hormone/follicle stimulating …
Kobayashi Award 2019: The neuroendocrine regulation of the mammalian reproduction
H Tsukamura - General and comparative endocrinology, 2022 - Elsevier
Mammalian reproductive function is a complex system of many players orchestrated by the
hypothalamus-pituitary–gonadal (HPG) axis. The hypothalamic gonadotropin-releasing …
hypothalamus-pituitary–gonadal (HPG) axis. The hypothalamic gonadotropin-releasing …
Conditional kisspeptin neuron-specific Kiss1 knockout with newly generated Kiss1-floxed and Kiss1-Cre mice replicates a hypogonadal phenotype of global Kiss1 …
The present study aimed to evaluate whether novel conditional kisspeptin neuron-specific
Kiss1 knockout (KO) mice utilizing the Cre-loxP system could recapitulate the infertility of …
Kiss1 knockout (KO) mice utilizing the Cre-loxP system could recapitulate the infertility of …
Male animal sterilization: history, current practices, and potential methods for replacing castration
Sterilization and castration have been synonyms for thousands of years. Making an animal
sterile meant to render them incapable of producing offspring. Castration or the physical …
sterile meant to render them incapable of producing offspring. Castration or the physical …
Mating-induced increase in Kiss1 mRNA expression in the anteroventral periventricular nucleus prior to an increase in LH and testosterone release in male rats
Y Watanabe, K Ikegami, S Nakamura… - … of Reproduction and …, 2020 - jstage.jst.go.jp
Kisspeptin has an indispensable role in gonadotropin-releasing hormone/gonadotropin
secretion in mammals. In rodents, kisspeptin neurons are located in distinct brain regions …
secretion in mammals. In rodents, kisspeptin neurons are located in distinct brain regions …
Modeling epileptic spasms during infancy: Are we heading for the treatment yet?
L Velíšek, J Velíšková - Pharmacology & therapeutics, 2020 - Elsevier
Infantile spasms (IS or epileptic spasms during infancy) were first described by Dr. William
James West (aka West syndrome) in his own son in 1841. While rare by definition (occurring …
James West (aka West syndrome) in his own son in 1841. While rare by definition (occurring …
Single neonatal estrogen implant sterilizes female animals by decreasing hypothalamic KISS1 expression
Reproductive sterilization by surgical gonadectomy is strongly advocated to help manage
animal populations, especially domesticated pets, and to prevent reproductive behaviors …
animal populations, especially domesticated pets, and to prevent reproductive behaviors …
Effect of diet-induced obesity on kisspeptin-neurokinin B-dynorphin A neurons in the arcuate nucleus and luteinizing hormone secretion in sex hormone-primed male …
S Minabe, K Iwata, H Tsuchida, H Tsukamura… - Peptides, 2021 - Elsevier
Metabolic stress resulting from either lack or excess of nutrients often causes infertility in
both sexes. Kisspeptin-neurokinin B-dynorphin A (KNDy) neurons in the arcuate nucleus …
both sexes. Kisspeptin-neurokinin B-dynorphin A (KNDy) neurons in the arcuate nucleus …
Pituitary glycoprotein hormones in human milk before and after pasteurization or refrigeration
Our aims were to investigate the presence of pituitary glycoprotein hormones in preterm and
donor milk, and to examine the effects of Holder pasteurization and refrigeration on the …
donor milk, and to examine the effects of Holder pasteurization and refrigeration on the …