Huntington disease: a quarter century of progress since the gene discovery

CM Testa, J Jankovic - Journal of the neurological sciences, 2019 - Elsevier
Huntington disease (HD) is an autosomal dominant neurodegenerative disorder
characterized by motor, behavioral, and cognitive manifestations. It is caused by an …

Huntington's disease

AD Ha, VSC Fung - Current opinion in neurology, 2012 - journals.lww.com
With predictive testing allowing the identification of gene-positive individuals prior to disease
onset, the prodromal stage of Huntington's disease provides an ideal period for the use of …

Analysis of gait and balance through a single triaxial accelerometer in presymptomatic and symptomatic Huntington's disease

A Dalton, H Khalil, M Busse, A Rosser, R van Deursen… - Gait & posture, 2013 - Elsevier
PURPOSE: To investigate the capacity of a single triaxial accelerometer sensor in detecting
gait and balance impairments in pre-manifest and manifest Huntington's disease (HD) …

Gait, balance, and falls in Huntington disease

K Vuong, CG Canning, JC Menant, CT Loy - Handbook of clinical neurology, 2018 - Elsevier
Huntington disease (HD) is an autosomal-dominant, progressive, neurodegenerative
disorder, characterized by involuntary movements and other motor impairments …

Task-specific training in Huntington disease: a randomized controlled feasibility trial

L Quinn, K Debono, H Dawes, AE Rosser… - Physical …, 2014 - academic.oup.com
Background Task-specific training may be a suitable intervention to address mobility
limitations in people with Huntington disease (HD). Objective The aim of this study was to …

Slower reaction and response times and impaired hand-eye coordination in individuals with neck pain

K Sittikraipong, P Silsupadol, S Uthaikhup - Musculoskeletal Science and …, 2020 - Elsevier
Background Neck pain is associated with sensorimotor dysfunction. Research is sparse of
the effect of neck pain on reaction and response times and hand-eye coordination …

Introduction of a complex reaction time tester instrument

RR Zana, A Zelei - Periodica Polytechnica Mechanical Engineering, 2020 - pp.bme.hu
The reaction time, which is also referred as reflex delay in the literature, is an important
factor in human balancing, since reaction time highly affects the ability of self stabilization …

[HTML][HTML] Timed up and go test with a cognitive task: correlations with neuropsychological measures in people with Parkinson's disease

K Çekok, T Kahraman, G Duran, BD Çolakoğlu… - Cureus, 2020 - ncbi.nlm.nih.gov
Background The Timed Up and Go (TUG) test is a simple and widely used clinical test for the
assessment of lower extremity function, balance, mobility, and fall risk in various …

Therapy in Huntington's disease: where are we?

MA Nance - Current neurology and neuroscience reports, 2012 - Springer
As of 2012, almost 20 years after the discovery of the causative gene, clinical research has
yet to find a disease-modifying treatment for Huntington's disease. However, both …

Postural stability limits in manifest and premanifest Huntington's disease under different sensory conditions

M Blanchet, F Prince, S Chouinard, J Messier - Neuroscience, 2014 - Elsevier
Increasing evidence indicates that Huntington's disease (HD) produces postural control
impairments even before the clinical diagnosis. It has been suggested that postural …