Bacterial and viral coinfections with the human respiratory syncytial virus

GA Pacheco, NMS Gálvez, JA Soto, CA Andrade… - Microorganisms, 2021 - mdpi.com
The human respiratory syncytial virus (hRSV) is one of the leading causes of acute lower
respiratory tract infections in children under five years old. Notably, hRSV infections can give …

Functional impairment of mononuclear phagocyte system by the human respiratory syncytial virus

K Bohmwald, JA Espinoza, RA Pulgar, EL Jara… - Frontiers in …, 2017 - frontiersin.org
The mononuclear phagocyte system (MPS) comprises of monocytes, macrophages (MΦ),
and dendritic cells (DCs). MPS is part of the first line of immune defense against a wide …

Biomarkers of respiratory syncytial virus (RSV) infection: specific neutrophil and cytokine levels provide increased accuracy in predicting disease severity

PM Brown, DL Schneeberger, G Piedimonte - Paediatric respiratory …, 2015 - Elsevier
Despite fundamental advances in the research on respiratory syncytial virus (RSV) since its
initial identification almost 60 years ago, recurring failures in developing vaccines and …

Modulation of host immunity by human respiratory syncytial virus virulence factors: a synergic inhibition of both innate and adaptive immunity

G Canedo-Marroquín, O Acevedo-Acevedo… - Frontiers in cellular …, 2017 - frontiersin.org
The Human Respiratory Syncytial Virus (hRSV) is a major cause of acute lower respiratory
tract infections (ARTIs) and high rates of hospitalizations in children and in the elderly …

Increased Heme Oxygenase 1 Expression upon a Primary Exposure to the Respiratory Syncytial Virus and a Secondary Mycobacterium bovis Infection

G Canedo-Marroquín, JA Soto, CA Andrade, SM Bueno… - Antioxidants, 2022 - mdpi.com
The human respiratory syncytial virus (hRSV) is the leading cause of severe lower
respiratory tract infections in infants. Because recurrent epidemics based on reinfection …

Immunological, viral, environmental, and individual factors modulating lung immune response to respiratory syncytial virus

S Vandini, P Bottau, G Faldella… - BioMed Research …, 2015 - Wiley Online Library
Respiratory syncytial virus is a worldwide pathogen agent responsible for frequent
respiratory tract infections that may become severe and potentially lethal in high risk infants …

Inflammatory damage on respiratory and nervous systems due to hRSV infection

K Bohmwald, JA Espinoza, D Becerra, K Rivera… - Current Opinion in …, 2015 - Elsevier
Highlights•We discuss about how interferons contribute at controlling viral infection.•We
discuss the role of IL-17 in lungs damage due to hRSV infection.•We consider the …

New insights contributing to the development of effective vaccines and therapies to reduce the pathology caused by hRSV

NMS Gálvez, JA Soto, AM Kalergis - International journal of molecular …, 2017 - mdpi.com
Human Respiratory Syncytial Virus (hRSV) is one of the major causes of acute lower
respiratory tract infections (ALRTI) worldwide, leading to significant levels of …

Small hydrophobic protein of respiratory syncytial virus as a novel vaccine antigen

B Schepens, M Schotsaert, X Saelens - Immunotherapy, 2015 - Taylor & Francis
Our studies have explored an alternative antibodyaccessible HRSV antigen; the ectodomain
of the small hydrophobic protein (SH). This membrane protein comprises 64 (HRSV …

Virus genes and host correlates of pathology are markedly reduced during respiratory syncytial and influenza virus co-infection in BALB/c mice

OT Ayegbusi, OA Ajagbe, TO Afowowe, AT Aransi… - Heliyon, 2019 - cell.com
Globally, influenza A virus (IAV) and respiratory syncytial virus (RSV) infection remain very
high. There is also a high burden of IAV and RSV co-infection in developing countries. To …