Nuclear import receptors directly bind to arginine-rich dipeptide repeat proteins and suppress their pathological interactions
S Hutten, S Usluer, B Bourgeois, F Simonetti, HM Odeh… - Cell reports, 2020 - cell.com
Nuclear import receptors, also called importins, mediate nuclear import of proteins and
chaperone aggregation-prone cargoes (eg, neurodegeneration-linked RNA-binding …
chaperone aggregation-prone cargoes (eg, neurodegeneration-linked RNA-binding …
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility
L Fumagalli, FL Young, S Boeynaems, M De Decker… - Science …, 2021 - science.org
A hexanucleotide repeat expansion in the C9orf72 gene is the most common genetic cause
of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). How this mutation …
of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). How this mutation …
[PDF][PDF] C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility
MB Madan, D Raitcheva13, A McCampbell13… - scholar.archive.org
Hexanucleotide repeat expansions in the C9orf72 gene are the most common genetic cause
of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). How this mutation …
of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). How this mutation …