Role of oxylipins in the inflammatory-related diseases NAFLD, obesity, and type 2 diabetes

M Misheva, J Johnson, J McCullagh - Metabolites, 2022 - mdpi.com
Oxygenated polyunsaturated fatty acids (oxylipins) are bioactive molecules established as
important mediators during inflammation. Different classes of oxylipins have been found to …

Ozone-enabled fatty acid discovery reveals unexpected diversity in the human lipidome

JP Menzel, RSE Young, AH Benfield, JS Scott… - Nature …, 2023 - nature.com
Fatty acid isomers are responsible for an under-reported lipidome diversity across all
kingdoms of life. Isomers of unsaturated fatty acids are often masked in contemporary …

Options of the main derivatization approaches for analytical ESI and MALDI mass spectrometry

VG Zaikin, RS Borisov - Critical Reviews in Analytical Chemistry, 2022 - Taylor & Francis
The inclusion of preliminary chemical labeling (derivatization) in the analysis process by
such powerful and widespread methods as electrospray ionization (ESI) and matrix-assisted …

[图书][B] Liquid chromatography: applications

S Fanali, PR Haddad, C Poole, ML Riekkola - 2017 - books.google.com
Liquid Chromatography: Applications, Second Edition, is a single source of authoritative
information on all aspects of the practice of modern liquid chromatography. It gives those …

Integrating the potential of ion mobility spectrometry-mass spectrometry in the separation and structural characterisation of lipid isomers

SM Camunas-Alberca, M Moran-Garrido… - Frontiers in Molecular …, 2023 - frontiersin.org
It is increasingly evident that a more detailed molecular structure analysis of isomeric lipids
is critical to better understand their roles in biological processes. The occurrence of isomeric …

Derivatization procedures and their analytical performances for HPLC determination in bioanalysis

V David, SC Moldoveanu… - Biomedical …, 2021 - Wiley Online Library
Derivatization, or chemical structure modification, is often used in bioanalysis performed by
liquid chromatography technique in order to enhance detectability or to improve the …

Recent developments in data acquisition, treatment and analysis with ion mobility‐mass spectrometry for lipidomics

M Moran‐Garrido, SM Camunas‐Alberca… - …, 2022 - Wiley Online Library
Lipids are involved in many biological processes and their study is constantly increasing. To
identify a lipid among thousand requires of reliable methods and techniques. Ion Mobility …

Microfluidic mixer for in situ ammonia analysis of single cells in mass spectrometry

X Yi, Q Zhang, T Xie, S Feng, N Xu, JM Lin - Analytical Chemistry, 2023 - ACS Publications
Mass spectrometry (MS) is a powerful tool for exploring single-cell heterogeneity. However,
due to the ultralow absolute content of most substances in a single cell, existing methods …

Esterified Oxylipins: Do They Matter?

CE Annevelink, RE Walker, GC Shearer - Metabolites, 2022 - mdpi.com
Oxylipins are oxygenated metabolites of fatty acids that share several similar biochemical
characteristics and functions to fatty acids including transport and trafficking. Oxylipins are …

The role of oxylipins and their validation as biomarkers in the clinical context

SM Camunas-Alberca, M Moran-Garrido, J Sáiz… - TrAC Trends in …, 2023 - Elsevier
Oxylipins are bioactive lipid mediators that participate in a wide range of processes, from
blood flow to inflammation. In recent years, their exhaustive characterization as potential …