Pediatric adenovirus pneumonia: clinical practice and current treatment

J Zhang, Y Zhu, Y Zhou, F Gao, X Qiu, J Li… - Frontiers in …, 2023 - frontiersin.org
Adenovirus pneumonia is common in pediatric upper respiratory tract infection, which is
comparatively easy to develop into severe cases and has a high mortality rate with many …

CRISPR-Cas13 in malaria parasite: Diagnosis and prospective gene function identification

E Quansah, Y Chen, S Yang, J Wang, D Sun… - Frontiers in …, 2023 - frontiersin.org
Malaria caused by Plasmodium is still a serious public health problem. Genomic editing is
essential to understand parasite biology, elucidate mechanical pathways, uncover gene …

RNA extraction-free workflow integrated with a single-tube CRISPR-Cas-based colorimetric assay for rapid SARS-CoV-2 detection in different environmental matrices

Y Kang, J Wang, W Zhang, Y Xu, B Xu, G Qu… - Journal of Hazardous …, 2023 - Elsevier
On-site environmental surveillance of viruses is increasingly important for infection
prevention and pandemic control. Herein, we report a facile single-tube colorimetric assay …

A CRISPR/Cas12a-based fluorescence aptasensor for the rapid and sensitive detection of ampicillin

BJ Yee, NF Shafiqah, NF Mohd-Naim… - International Journal of …, 2023 - Elsevier
This study introduces CRISPR/Cas-based aptasensor for the highly sensitive and specific
detection of the antibiotic, ampicillin. Ampicillin (AMPI) is a commonly used antibiotic for …

Systemic delivery of specific and efficient CRISPR/Cas9 system targeting HPV16 oncogenes using LL‐37 antimicrobial peptide in C57BL/6 mice

N Khairkhah, A Bolhassani, F Rajaei… - Journal of Medical …, 2023 - Wiley Online Library
Human papillomavirus (HPV) type 16 is the most common sexually transmitted virus related
to cervical cancer. Among different types of advanced novel therapies, the clustered …

Bioengineering of fungal endophytes through the CRISPR/Cas9 system

V Verma, A Batta, HB Singh, A Srivastava… - Frontiers in …, 2023 - frontiersin.org
The CRISPR/Cas9 system is a genome-editing tool that allows for precise and efficient
modifications to the DNA of a cell. This technology can be used in endophytic fungi, which …

[HTML][HTML] Emerging Applications of Biomedical Science in Pandemic Prevention and Control: A Review

IN Weerarathna, A Luharia, S Tivaskar, FA Nankong… - Cureus, 2023 - ncbi.nlm.nih.gov
The COVID-19 pandemic has made it abundantly clear how crucial biomedical science is to
pandemic control and prevention on a global scale. The importance of biomedical science in …

Revolutionizing digestive system tumor organoids research: Exploring the potential of tumor organoids

Z Xiu, Q Yang, F Xie, F Han, W He… - Journal of Tissue …, 2024 - journals.sagepub.com
Digestive system tumors are the leading cause of cancer-related deaths worldwide. Despite
ongoing research, our understanding of their mechanisms and treatment remain …

LncRNA-mediated cartilage homeostasis in osteoarthritis: a narrative review

L Zhang, H Zhang, Q Xie, H Feng, H Li, Z Li… - Frontiers in …, 2024 - frontiersin.org
Osteoarthritis (OA) is a degenerative disease of cartilage that affects the quality of life and
has increased in morbidity and mortality in recent years. Cartilage homeostasis and …

In vitro study of HPV18-positive cervical cancer HeLa cells based on CRISPR/Cas13a system

A Zhang, X Zheng, S Chen, G Duan - Gene, 2024 - Elsevier
The E6 protein is a known oncogene in cervical cancer and plays a key role in the
development and progression of cervical cancer by reducing the expression level of the …