[HTML][HTML] Hydrogels as drug delivery systems: A review of current characterization and evaluation techniques

M Vigata, C Meinert, DW Hutmacher, N Bock - Pharmaceutics, 2020 - mdpi.com
Owing to their tunable properties, controllable degradation, and ability to protect labile
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …

Production of hydrogel microparticles in microfluidic devices: a review

A Moreira, J Carneiro, J Campos… - Microfluidics and …, 2021 - Springer
Hydrogels are biocompatible materials commonly used in biological applications, such as
cell encapsulation, tissue engineering and drug delivery systems. The use of hydrogels in …

Development and performance of a 3D‐printable poly (ethylene glycol) diacrylate hydrogel suitable for enzyme entrapment and long‐term biocatalytic applications

B Schmieg, A Schimek… - Engineering in Life …, 2018 - Wiley Online Library
Physical entrapment of enzymes within a porous matrix is a fast and gentle process to
immobilize biocatalysts to enable their recycling and long‐term use. This study introduces …

Enzyme scaffolds with hierarchically defined properties via 3D jet writing

A Steier, B Schmieg… - Macromolecular …, 2020 - Wiley Online Library
The immobilization of enzymes into polymer hydrogels is a versatile approach to improve
their stability and utility in biotechnological and biomedical applications. However, these …

Determining Rates of Molecular Secretion from Supernatant Concentration Measurements in a 3D-Bioprinted Human Liver Tissue Model

MR Anjum, V Subramaniam, BR Higgins… - ACS Biomaterials …, 2024 - ACS Publications
The secretion rate of albumin is a key indicator of function in liver tissue models used for
hepatotoxicity and pharmacokinetic testing. However, it is not generally clear how to …

Interplay between flow and diffusion in capillary alginate hydrogels

E Schuster, K Sott, A Ström, A Altskär, N Smisdom… - Soft Matter, 2016 - pubs.rsc.org
Alginate gels with naturally occurring macroscopic capillaries have been used as a model
system to study the interplay between laminar flow and diffusion of nanometer-sized solutes …

[HTML][HTML] Application of 3-D microfluidic models for studying mass transport properties of the tumor interstitial matrix

A Avendano, M Cortes-Medina… - Frontiers in Bioengineering …, 2019 - frontiersin.org
The physical remodeling associated with cancer progression results in barriers to mass
transport in the tumor interstitial space. This hindrance ultimately affects the distribution of …

[HTML][HTML] Lecithin as an effective modifier of the transport properties of variously crosslinked hydrogels

R Heger, N Zinkovska, M Trudicova, M Kadlec, M Pekar… - Gels, 2023 - mdpi.com
Transport properties are one of the most crucial assets of hydrogel samples, influencing their
main application potential, ie, as drug carriers. Depending on the type of drug or the …

Characterizing properties of polymers and colloids by their reaction-diffusion behavior in microfluidic channels

A Bezrukov, Y Galyametdinov - Colloids and Surfaces A: Physicochemical …, 2021 - Elsevier
Molecular mobility is a key factor that determines the behavior of supramolecular systems in
various applications such as drug delivery. Characterizing transport properties of such …

Evidence of superdiffusive nanoscale motion in anionic polymeric hydrogels: Analysis of PGSE-NMR data and comparison with drug release properties

F Castiglione, M Casalegno, M Ferro, F Rossi… - Journal of Controlled …, 2019 - Elsevier
Polymeric hydrogels are promising candidates for drug delivery applications, thanks to their
ability to encapsulate, transport and release a wide range of chemicals. The successful …