Docking methodology aims to predict the experimental binding modes and affinities of small
molecules within the binding site of particular receptor targets and is currently used as a …

Protein-ligand docking is currently an important tool in drug discovery efforts and an active
area of research that has been the subject of important developments over the last decade …

Among the few non-structural proteins encoded by the picornaviral genome, the 2A protein
is particularly special, irrespective of structure or function. During the evolution of the …

The aspartate protease of the human immune deficiency type-1 virus (HIV-1) has become a
crucial antiviral target in which many useful antiretroviral inhibitors have been developed …

The rates of infections and onsets of diseases are increasing day by day. With the passage
of time, new microbial pathogenic strains are evolving and they claim the lives of thousands …

ABSTRACT HIV/AIDs is a prevalent disease infecting millions of people throughout the
world. Although a lot of improvement has been achieved over the year in regard to the …

As doenças tropicais negligenciadas, que atingem as populações mais carentes do mundo,
representam em termos humanitários e socioeconômicos uma grande preocupação global …