Ferroptosis, a form of regulated cell death, is initiated by oxidative perturbations of the
intracellular microenvironment, which is under the constitutive control of glutathione …

The maintenance of iron homeostasis is essential for proper endocrine function. A growing
body of evidence suggests that iron imbalance is a key factor in the development of several …

Ferroptosis is an iron-dependent, oxidative cell death, and is characterized by iron-
dependent accumulation of reactive oxygen species (ROS) within the cell. It has been …

Iron is a transition metal and essential constituent of almost all living cells and organisms. As
component of various metalloproteins it is involved in critical biochemical processes such as …

Dental enamel is the hardest and most mineralized tissue in extinct and extant vertebrate
species and provides maximum durability that allows teeth to function as weapons and/or …

Ferroptosis is a form of oxidative cell death and has become a chemotherapeutic target for
cancer treatment. BAY 11–7085 (BAY), which is a well-known IκBα inhibitor, suppressed …

Obesity is an excessive adipose tissue accumulation that may have detrimental effects on
health. Particularly, childhood obesity has become one of the main public health problems in …

Ferroptosis is an iron-dependent, oxidative cell death, and is distinct from apoptosis,
necrosis and autophagy. In this study, we demonstrated that lysosome disrupting agent …

Iron accumulation is a key mediator of several cytotoxic mechanisms leading to the
impairment of redox homeostasis and cellular death. Iron overload is often associated with …

The development of targeted nanomedicines for cancer therapy has been an utmost focus of
research across different fields including materials science, nanotechnology, biotechnology …