Abstract Silence information regulator 1 (SIRT1), a member of the sirtuin family, targets
histones and many non-histone proteins and participates in various physiological functions …

Insulin, a key pleiotropic hormone, regulates metabolism through several signaling
pathways in target tissues including skeletal muscle, liver, and brain. In the brain, insulin …

Diet is the only known intervention which has been conclusively shown to extend life span. It
can be argued the key role diet has to play in the aging process came to prominence as a …

Dementia is defined as a gradual cognitive impairment that interferes with everyday tasks,
and is a leading cause of dependency, disability, and mortality. According to the current …

Personalised training of motor and cognitive abilities is fundamental to help older people
maintain a good quality of life, especially in case of frailty conditions. However, the training …

Creatine monohydrate (CrM) is one of the most widely used nutritional supplements among
active individuals and athletes to improve high-intensity exercise performance and training …

This paper reviews the potential role of glutathione (GSH) in autism spectrum disorder
(ASD). GSH plays a key role in the detoxification of xenobiotics and maintenance of balance …

Strong adherence to a Mediterranean diet is associated with improved cognitive function
and a lower prevalence of mild cognitive impairment. Olive oil and red wine are rich sources …

In the recent time, neurodegenerative disorders like Alzheimer disease were recognized for
their significant role in the current healthcare because of their growing incidence and costs …

Alzheimer's disease (AD) is one of the life-threatening neurodegenerative disorders in the
elderly (> 60 years) and incurable across the globe to date. AD is caused by the involvement …