The role of microglia in diabetic retinopathy: inflammation, microvasculature defects and neurodegeneration

C Altmann, MHH Schmidt - International journal of molecular sciences, 2018 - mdpi.com
Diabetic retinopathy is a common complication of diabetes mellitus, which appears in one
third of all diabetic patients and is a prominent cause of vision loss. First discovered as a …

Diabetic retinopathy: vascular and inflammatory disease

F Semeraro, A Cancarini, R dell'Omo… - Journal of diabetes …, 2015 - Wiley Online Library
Diabetic retinopathy (DR) is the leading cause of visual impairment in the working‐age
population of the Western world. The pathogenesis of DR is complex and several vascular …

Angiogenesis and inflammation crosstalk in diabetic retinopathy

M Capitão, R Soares - Journal of cellular biochemistry, 2016 - Wiley Online Library
Diabetic retinopathy (DR) is one of the most prevalent microvascular complications of
diabetes and one of the most frequent causes of blindness in active age. Etiopathogenesis …

The role of myeloid cells in the promotion of tumour angiogenesis

C Murdoch, M Muthana, SB Coffelt, CE Lewis - Nature reviews cancer, 2008 - nature.com
The use of various transgenic mouse models and analysis of human tumour biopsies has
shown that bone marrow-derived myeloid cells, such as macrophages, neutrophils …

Resolvin E1 regulates inflammation at the cellular and tissue level and restores tissue homeostasis in vivo

H Hasturk, A Kantarci, E Goguet-Surmenian… - The Journal of …, 2007 - journals.aai.org
Abstract Resolvin E1 (RvE1) is a potent proresolving mediator of inflammation derived from
omega-3 eicosapentaenoic acid that acts locally to stop leukocyte recruitment and promote …

[HTML][HTML] Oncometabolites lactate and succinate drive pro-angiogenic macrophage response in tumors

MMG Kes, J Van den Bossche, AW Griffioen… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Macrophages are innate phagocytic leukocytes that are highly present in solid tumors,
where they are referred to as tumor-associated macrophages (TAMs). In solid tumors, the …

The role IL-1 in tumor-mediated angiogenesis

E Voronov, Y Carmi, RN Apte - Frontiers in physiology, 2014 - frontiersin.org
Tumor angiogenesis is one of the hallmarks of tumor progression and is essential for
invasiveness and metastasis. Myeloid inflammatory cells, such as immature myeloid …

Human vitreous in proliferative diabetic retinopathy: characterization and translational implications

IM Nawaz, S Rezzola, A Cancarini, A Russo… - Progress in retinal and …, 2019 - Elsevier
Diabetic retinopathy (DR) is one of the leading causes of visual impairment in the working-
age population. DR is a progressive eye disease caused by long-term accumulation of …

The impact of the immune system on tumor: angiogenesis and vascular remodeling

C Stockmann, D Schadendorf, R Klose… - Frontiers in oncology, 2014 - frontiersin.org
Angiogenesis, the formation of new blood vessels, as well as inflammation with massive
infiltration of leukocytes are hallmarks of various tumor entities. Various epidemiological …

Plasma osteopontin levels and expression in adipose tissue are increased in obesity

J Gomez-Ambrosi, V Catalan, B Ramirez… - The Journal of …, 2007 - academic.oup.com
Context: Obesity acts as a cardiovascular risk factor by mechanisms that are not fully
understood. Osteopontin (OPN) is a proinflammatory mediator involved in tissue remodeling …