The vagus nerve has an important role in regulation of metabolic homeostasis, and efferent
vagus nerve-mediated cholinergic signalling controls immune function and proinflammatory …

Glycated haemoglobin (HbA1c) is currently the gold standard for glucose monitoring in
patients with diabetes, and has been increasingly adopted as a criteria for diabetes …

Insulin resistance plays a role in the pathogenesis of diabetes, including gestational
diabetes. The glucose clamp is considered the gold standard for determining in vivo insulin …

Rationale and Objectives: Although many clinical physiology and epidemiology studies
show an association between obstructive sleep apnea (OSA) and markers of insulin …

Increased sympathetic activity is a well-known pathophysiological mechanism in insulin
resistance (IR) and hypertension (HT). The carotid bodies (CB) are peripheral …

Diabetes is associated with an increased risk for brain disorders, namely cognitive
impairments associated with hippocampal dysfunction underlying diabetic encephalopathy …

Increased sugar consumption, especially fructose, is strongly related to the development of
type 2 diabetes (T2D) and metabolic syndrome. The aim of this study was to evaluate long …

We tested the hypothesis that long-term caffeine intake prevents the development of insulin
resistance and hypertension in two pathological animal models: the high-fat (HF) and the …

Background Diabetic cardiomyopathy (DCM) is defined as structural and functional changes
in the myocardium due to metabolic and cellular abnormalities induced by diabetes mellitus …

Aims/hypothesis We recently described that carotid body (CB) over-activation is involved in
the aetiology of insulin resistance and arterial hypertension in animal models of the …