Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Highlights•Nitric oxide plays diverse roles in host–pathogen interactions including both
direct antimicrobial actions and regulation of the host immune response.•Nitric oxide …

Rationale: The heart undergoes dramatic developmental changes during the prenatal to
postnatal transition, including maturation of cardiac myocyte energy metabolic and …

Estrogen-related receptors (ERR) α and γ were shown recently to serve as regulators of
cardiac maturation, yet the underlying mechanisms have not been delineated. Herein, we …

Abstract Treatment of Staphylococcus aureus infections is a constant challenge due to
emerging resistance to vancomycin, a last-resort drug. S-nitrosylation, the covalent …

Staphylococcus aureus can utilize exogenous fatty acids for phospholipid synthesis. The
fatty acid kinase FakA is essential for this utilization by phosphorylating exogenous fatty …

Abstract Isocitrate dehydrogenase 2 (IDH2) is an NADP+-dependent enzyme that catalyzes
the oxidative decarboxylation of isocitrate to α-ketoglutarate in the mitochondrial matrix, and …

Staphylococcus aureus colonizes the nares of approximately 30% of humans, a risk factor
for opportunistic infections. To gain insight into S. aureus virulence potential in the …

Respiratory mutants, both naturally occurring and genetically constructed, have taught us
about the importance of metabolism in influencing virulence factor production, persistence …

Nitric oxide (NO) is a small ubiquitous gaseous molecule that has been found in many host-
pathogen interactions. NO has been shown to be part of the defense arsenal of animal cells …