Dendrimers are globular structures, presenting an initiator core, repetitive layers starting
radially from the core and terminal groups on the surface, resembling tree architecture …

Adrenoleukodystrophy (ALD) is a rare X‐linked disease caused by a mutation of the
peroxisomal ABCD1 gene. This review summarizes our current understanding of the …

Hyperinflammation triggered by SARS-CoV-2 is a major cause of disease severity, with
activated macrophages implicated in this response. OP-101, a hydroxyl-polyamidoamine …

Highlights•This review article offers an in-depth overview of significant advances in the field
of antioxidative nanotechnology.•The pathology and molecular mechanisms of oxidative …

Retinal Müller glia function as injury-induced stem-like cells in zebrafish but not mammals.
However, insights gleaned from zebrafish have been applied to stimulate nascent …

Cognitive impairment is a common aspect of multiple sclerosis (MS) for which there are no
treatments. Reduced brain N-acetylaspartylglutamate (NAAG) levels are linked to impaired …

N-acetylcysteine (NAC), a precursor of cysteine and, thereby, glutathione (GSH), acts as an
antioxidant through a variety of mechanisms, including oxidant scavenging, GSH …

Abstract X-Adrenoleukodystrophy (X-ALD) and its adult-onset, most prevalent variant
adrenomyeloneuropathy (AMN) are caused by mutations in the peroxisomal transporter of …

X-linked adrenoleukodystrophy (ALD) is a genetic disorder that presents neurologically as
either a rapid and fatal cerebral demyelinating disease in childhood (childhood cerebral …

Retinal microglial/macrophage activation and optic nerve (ON) microglial/macrophage
activation are glaucoma biomarkers and potential therapeutic targets for this blinding …