Phytomedicines and nutraceuticals: alternative therapeutics for sickle cell anemia

NA Imaga - The scientific world journal, 2013 - Wiley Online Library
Sickle cell anemia is a genetically inherited disease in which the “SS” individual possesses
an abnormal beta globin gene. A single base substitution in the gene encoding the human β …

A Review of Parquetina nigrescens (Afzel.) Bullock, A Plant for Traditional Medicine: Phytochemical and Pharmacological Properties

E Adase, P Ankutse, D Kumadoh… - Evidence‐Based …, 2022 - Wiley Online Library
The development of herbal medicines as a remedy for several illnesses has been
recognized and accepted worldwide by health experts. Parquetina nigrescens is a perennial …

Antisickling property of Carica papaya leaf extract

NOA Imaga, GO Gbenle, VI Okochi, SO Akanbi… - 2009 - ir.unilag.edu.ng
Sickle cell disease (SCD) results from a mutation in the hemoglobin inside the red blood
cells, where a glutamic acid at position 6 is replaced by a valine. Many phytomedicines have …

Ethnomedicinal survey of medicinal plants used in the management of sickle cell disorder in Southern Nigeria

OO Amujoyegbe, M Idu, JM Agbedahunsi… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance The present study entails the medicinal plant species used
to manage sickle cell disorder in Southern States of Nigeria. Materials and methods The …

Antisickling and toxicological profiles of leaf and stem of Parquetina nigrescens L.

NOA Imaga, GO Gbenle, VI Okochi, SO Adenekan… - 2010 - ir.unilag.edu.ng
Folk medicine reportedly uses Parquetina nigrescens L.(Asclepiadaceae) as a herbal
remedy for the management of sickle cell anemia. This study was carried out to screen the …

[HTML][HTML] Sodium metabisulfite–induced polymerization of sickle cell hemoglobin incubated in the extracts of three medicinal plants (Anacardium occidentale, Psidium …

PC Chikezie - Pharmacognosy magazine, 2011 - ncbi.nlm.nih.gov
Background: The exploitation and utilization of vast varieties of herbal extracts may serve as
alternative measures to deter aggregation of deoxygenated sickle cell hemoglobin …

The use of phytomedicines as effective therapeutic agents in sickle cell anemia

NOA Imaga - 2010 - ir.unilag.edu.ng
Medicinal plants are parts of a plant or the whole plant that possess healing properties and
unlike orthodox (synthetic) medicines, which may have adverse side effects, medicinal plant …

Analyses of antisickling potency of Carica papaya dried leaf extract and fractions

NA Imaga, OA Adepoju - 2010 - ir.unilag.edu.ng
Carica papaya dried leaves have been indicated in sickle cell anemia management by local
indigenous folk and in recent scientific research. In this research, dried C. papaya leaves …

[PDF][PDF] Aphrodisiac and male sexual characteristics in albino rats treated with the aqueous extract of Parquetina nigrescens root

OT Oyelowo, OV Fabiyi, OM Jimoh… - Nigerian Journal of …, 2014 - researchgate.net
The use of plants and herbs to boost libido, induce erection, and as an aphrodisiac agent
has been in existence for long. The root of Parquetina nigrescens is one of such acclaimed …

[HTML][HTML] Safety and toxicity of aqueous leaf extracts of Camellia sinensis, Parquetina nigrescens and Telfairia occidentalis in mice

OL Olayinka, EAG Khalil, SA Atunwa… - African Journal of …, 2018 - academicjournals.org
Plant extracts as potential phytotherapeutic products are supposed to be safe. However,
adverse and untoward fatal effects have been reported. Study aimed to evaluate the safety …