Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …

The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

Mendelian randomisation (MR) studies allow a better understanding of the causal effects of
modifiable exposures on health outcomes, but the published evidence is often hampered by …

Abstract The coronavirus disease 2019 (COVID-19) pandemic has led to a declaration of a
Public Health Emergency of International Concern by the World Health Organization. As of …

Skeletal muscle is a major organ of insulin-induced glucose metabolism. In addition, loss of
muscle mass is closely linked to insulin resistance (IR) and metabolic syndrome (Met-S) …

Abstract Purpose of Review Evidence from observational studies suggests that obesity is
associated with low vitamin D. As both obesity and hypovitaminosis D present an alarmingly …

There are variable definitions of vitamin D deficiency, based on different thresholds of serum
25-hydroxyvitamin D (25 (OH) D); this has a major bearing on the prevalence estimates of …

Vitamin D deficiency can lead to musculoskeletal diseases such as rickets and
osteomalacia, but vitamin D supplementation may also prevent extraskeletal diseases such …

Multiple sclerosis is a complex autoimmune disease, and several therapies for multiple
sclerosis have been developed and widely used. However, existing medications for multiple …

The pleiotropic role of vitamin D has been explored over the past decades and there is
compelling evidence for an epidemiological association between poor vitamin D status and …