The human connectome in Alzheimer disease—relationship to biomarkers and genetics
The pathology of Alzheimer disease (AD) damages structural and functional brain networks,
resulting in cognitive impairment. The results of recent connectomics studies have now …
resulting in cognitive impairment. The results of recent connectomics studies have now …
[HTML][HTML] Resting-state connectivity in neurodegenerative disorders: Is there potential for an imaging biomarker?
Biomarkers in whichever modality are tremendously important in diagnosing of disease,
tracking disease progression and clinical trials. This applies in particular for disorders with a …
tracking disease progression and clinical trials. This applies in particular for disorders with a …
Network dysfunction in Alzheimer's disease: refining the disconnection hypothesis
Much effort in recent years has focused on understanding the effects of Alzheimer's disease
(AD) on neural function. This effort has resulted in an enormous number of papers …
(AD) on neural function. This effort has resulted in an enormous number of papers …
[HTML][HTML] Aberrant intra-and inter-network connectivity architectures in Alzheimer's disease and mild cognitive impairment
Alzheimer's disease (AD) patients and those with high-risk mild cognitive impairment are
increasingly considered to have dysfunction syndromes. Large-scale network studies based …
increasingly considered to have dysfunction syndromes. Large-scale network studies based …
[HTML][HTML] Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease
Prior studies of aging and Alzheimer disease have evaluated resting state functional
connectivity (FC) using either seed-based correlation (SBC) or independent component …
connectivity (FC) using either seed-based correlation (SBC) or independent component …
Functional connectivity in autosomal dominant and late-onset Alzheimer disease
Importance Autosomal dominant Alzheimer disease (ADAD) is caused by rare genetic
mutations in 3 specific genes in contrast to late-onset Alzheimer disease (LOAD), which has …
mutations in 3 specific genes in contrast to late-onset Alzheimer disease (LOAD), which has …
Atrophy in Alzheimer's disease and semantic dementia: an ALE meta-analysis of voxel-based morphometry studies
M Chapleau, J Aldebert… - Journal of …, 2016 - content.iospress.com
Background/Objectives: Alzheimer's disease (AD) and semantic dementia (SD) have distinct
episodic memory profiles despite the hippocampal atrophy that characterizes both diseases …
episodic memory profiles despite the hippocampal atrophy that characterizes both diseases …
[HTML][HTML] Differences on brain connectivity in adulthood are present in subjects with iron deficiency anemia in infancy
C Algarin, KD Karunakaran, S Reyes… - Frontiers in aging …, 2017 - frontiersin.org
Iron deficiency continues to be the most prevalent micronutrient deficit worldwide. Since iron
is involved in several processes including myelination, dopamine neurotransmission and …
is involved in several processes including myelination, dopamine neurotransmission and …
Cerebrospinal fluid Aβ42, phosphorylated Tau181, and resting-state functional connectivity
Importance Resting-state functional connectivity magnetic resonance imaging has great
potential for characterizing pathophysiological changes during the preclinical phase of …
potential for characterizing pathophysiological changes during the preclinical phase of …
[HTML][HTML] Altered intranetwork and internetwork functional connectivity in type 2 diabetes mellitus with and without cognitive impairment
SQ Yang, ZP Xu, Y Xiong, YF Zhan, LY Guo, S Zhang… - Scientific reports, 2016 - nature.com
Type 2 diabetes mellitus (T2DM) is associated with cognitive impairment. We investigated
whether alterations of intranetwork and internetwork functional connectivity with T2DM …
whether alterations of intranetwork and internetwork functional connectivity with T2DM …