Nitric oxide as a central molecule in hypertension: Focus on the vasorelaxant activity of new nitric oxide donors
GM da Silva, MC da Silva, DVG Nascimento… - Biology, 2021 - mdpi.com
Simple Summary Nitric oxide is an important molecule that performs a variety of functions in
our bodies, especially in the cardiovascular system. In certain pathological conditions, such …
our bodies, especially in the cardiovascular system. In certain pathological conditions, such …
The latest advances in the discovery of nitric oxide hybrid drug compounds
RAM Serafim, FG Pernichelle… - Expert Opinion on Drug …, 2017 - Taylor & Francis
Introduction: There is a great interest in Nitric oxide (NO) within medicinal chemistry since it's
involved in human signaling pathways. Prodrugs or hybrid compounds containing NO-donor …
involved in human signaling pathways. Prodrugs or hybrid compounds containing NO-donor …
[HTML][HTML] Proteolysis in goat “coalho” cheese supplemented with probiotic lactic acid bacteria
TKA Bezerra, ARR de Araujo, ES do Nascimento… - Food Chemistry, 2016 - Elsevier
This study aimed to analyse the proteolytic effects of adding isolated and combined probiotic
strains to goat “coalho” cheese. The cheeses were: QS–with culture Start, composed by …
strains to goat “coalho” cheese. The cheeses were: QS–with culture Start, composed by …
Apocynin reduces blood pressure and restores the proper function of vascular endothelium in SHR
This study has evaluated how the vascular endothelium of hypertensive rats chronically
treated with apocynin affects acetylcholine (ACh), sodium nitroprusside (SNP), and …
treated with apocynin affects acetylcholine (ACh), sodium nitroprusside (SNP), and …
Overview of antagonists used for determining the mechanisms of action employed by potential vasodilators with their suggested signaling pathways
This paper is a review on the types of antagonists and the signaling mechanism pathways
that have been used to determine the mechanisms of action employed for vasodilation by …
that have been used to determine the mechanisms of action employed for vasodilation by …
Gut microbiota perturbation in early life could Influence Pediatric blood pressure regulation in a sex-dependent manner in juvenile rats
Y Yang, J Li, Z Zhou, S Wu, J Zhao, W Jia, M Liu… - Nutrients, 2023 - mdpi.com
The present study aimed to investigate whether gut dysbiosis induced by ceftriaxone in early
life could influence pediatric blood pressure regulation in childhood with or without exposure …
life could influence pediatric blood pressure regulation in childhood with or without exposure …
[HTML][HTML] The novel organic mononitrate NDHP attenuates hypertension and endothelial dysfunction in hypertensive rats
LL Paulo, JC Cruz, Z Zhuge, A Carvalho-Galvão… - Redox Biology, 2018 - Elsevier
Rationale Development and progression of cardiovascular diseases, including
hypertension, are often associated with impaired nitric oxide synthase (NOS) function and …
hypertension, are often associated with impaired nitric oxide synthase (NOS) function and …
Apocynin alters redox signaling in conductance and resistance vessels of spontaneously hypertensive rats
Chronic treatment with apocynin reduces blood pressure and prevents endothelial
dysfunction development in spontaneously hypertensive rats (SHR). Mechanisms …
dysfunction development in spontaneously hypertensive rats (SHR). Mechanisms …
Anti-hypertensive property of a nickel-piperazine/NO donor in spontaneously hypertensive rats
The nickel-piperazine/NO donor compound, Ni (PipNONO) Cl, belonging to the family of
compounds labelled as metal-nonoates, due to its promising vasodilating activity, has …
compounds labelled as metal-nonoates, due to its promising vasodilating activity, has …
Nitric oxide signaling and the cross talk with prostanoids pathways in vascular system
BR Silva, TD Paula, M Paulo… - Medicinal …, 2017 - ingentaconnect.com
Background: This review provides an overview of the cellular signaling of nitric oxide (NO)
and prostanoids in vascular cells and the possible cross talk between their pathways, mainly …
and prostanoids in vascular cells and the possible cross talk between their pathways, mainly …