Effects of ionizing radiation on mitochondria
WWY Kam, RB Banati - Free Radical Biology and Medicine, 2013 - Elsevier
The current concept of radiobiology posits that damage to the DNA in the cell nucleus is the
primary cause for the detrimental effects of radiation. However, emerging experimental …
primary cause for the detrimental effects of radiation. However, emerging experimental …
Potential relationship between the biological effects of low-dose irradiation and mitochondrial ROS production
K Kawamura, F Qi, J Kobayashi - Journal of radiation research, 2018 - academic.oup.com
Exposure to ionizing radiation (IR) induces various types of DNA damage, of which DNA
double-strand breaks are the most severe, leading to genomic instability, tumorigenesis, and …
double-strand breaks are the most severe, leading to genomic instability, tumorigenesis, and …
Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition
H Mori, TC Prestwich, MA Reid… - The Journal of …, 2012 - Am Soc Clin Investig
Preadipocytes secrete several WNT family proteins that act through autocrine/paracrine
mechanisms to inhibit adipogenesis. The activity of WNT ligands is often decreased by …
mechanisms to inhibit adipogenesis. The activity of WNT ligands is often decreased by …
d-Galactose-induced oxidative stress and mitochondrial dysfunction in the cochlear basilar membrane: an in vitro aging model
B Guo, Q Guo, Z Wang, JB Shao, K Liu, ZD Du… - Biogerontology, 2020 - Springer
The cochlear basilar membrane (CBM) contains inner hair cells and outer hair cells that
convert sound waves into electrical signals and transmit them to the central auditory system …
convert sound waves into electrical signals and transmit them to the central auditory system …
Mitofusin 1 silencing decreases the senescent associated secretory phenotype, promotes immune cell recruitment and delays melanoma tumor growth after …
D Tarallo, J Martínez, A Leyva, A Mónaco, C Perroni… - Scientific Reports, 2024 - nature.com
Cellular senescence is a therapy endpoint in melanoma, and the senescence-associated
secretory phenotype (SASP) can affect tumor growth and microenvironment, influencing …
secretory phenotype (SASP) can affect tumor growth and microenvironment, influencing …
[HTML][HTML] Potential toxicity of quercetin: The repression of mitochondrial copy number via decreased POLG expression and excessive TFAM expression in irradiated …
R Chen, J Lin, J Hong, D Han, AD Zhang, R Lan, L Fu… - Toxicology Reports, 2014 - Elsevier
The cytotoxicity of quercetin is not well understood. Using an ICR murine model, we
unexpectedly found that mice exposed to 7 Gy total body irradiation (TBI) exhibited general …
unexpectedly found that mice exposed to 7 Gy total body irradiation (TBI) exhibited general …
Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells
J Martínez, D Tarallo, L Martínez-Palma… - Biochemical …, 2019 - portlandpress.com
Cellular senescence is an endpoint of chemotherapy, and targeted therapies in melanoma
and the senescence-associated secretory phenotype (SASP) can affect tumor growth and …
and the senescence-associated secretory phenotype (SASP) can affect tumor growth and …
Effects of X-irradiation on mitochondrial DNA damage and its supercoiling formation change
X Zhou, N Li, Y Wang, Y Wang, X Zhang, H Zhang - Mitochondrion, 2011 - Elsevier
There have been a small number of reports of radiation-induced mtDNA damage, and
mtDNA supercoiling formation change induced by ionizing radiation has not been …
mtDNA supercoiling formation change induced by ionizing radiation has not been …
ROS‐induced DNA damage associates with abundance of mitochondrial DNA in white blood cells of the untreated schizophrenic patients
IV Chestkov, EM Jestkova, ES Ershova… - Oxidative Medicine …, 2018 - Wiley Online Library
Objective. The aim of this study was (1) to examine the leukocyte mtDNA copy number (CN)
in unmedicated (SZ (m−)) and medicated (SZ (m+)) male patients with paranoid …
in unmedicated (SZ (m−)) and medicated (SZ (m+)) male patients with paranoid …
Ephedrine-induced mitophagy via oxidative stress in human hepatic stellate cells
AY Lee, Y Jang, SH Hong, SH Chang… - The Journal of …, 2017 - jstage.jst.go.jp
The herb Ephedra sinica (also known as Chinese ephedra or Ma Huang), used in traditional
Chinese medicine, contains alkaloids identical to ephedrine and pseudoephedrine as its …
Chinese medicine, contains alkaloids identical to ephedrine and pseudoephedrine as its …