Multifunctional gold nanoparticles: a novel nanomaterial for various medical applications and biological activities

X Hu, Y Zhang, T Ding, J Liu, H Zhao - Frontiers in Bioengineering …, 2020 - frontiersin.org
Nanotechnology has become a trending area in science and has made great advances with
the development of functional, engineered nanoparticles. Various metal nanoparticles have …

Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements

S Her, DA Jaffray, C Allen - Advanced drug delivery reviews, 2017 - Elsevier
Gold nanoparticles (AuNPs) have emerged as novel radiosensitizers owing to their high X-
ray absorption, synthetic versatility, and unique chemical, electronic and optical properties …

Gold nanoparticles for cancer radiotherapy: a review

K Haume, S Rosa, S Grellet, MA Śmiałek… - Cancer …, 2016 - Springer
Radiotherapy is currently used in around 50% of cancer treatments and relies on the
deposition of energy directly into tumour tissue. Although it is generally effective, some of the …

[HTML][HTML] Nanoparticles for radiation therapy enhancement: the key parameters

P Retif, S Pinel, M Toussaint, C Frochot, R Chouikrat… - Theranostics, 2015 - ncbi.nlm.nih.gov
This review focuses on the radiosensitization strategies that use high-Z nanoparticles. It
does not establish an exhaustive list of the works in this field but rather propose constructive …

Nanoparticle radio-enhancement: principles, progress and application to cancer treatment

Z Kuncic, S Lacombe - Physics in Medicine & Biology, 2018 - iopscience.iop.org
Enhancement of radiation effects by high-atomic number nanoparticles (NPs) has been
increasingly studied for its potential to improve radiotherapeutic efficacy. The underlying …

Physical basis and biological mechanisms of gold nanoparticle radiosensitization

KT Butterworth, SJ McMahon, FJ Currell, KM Prise - Nanoscale, 2012 - pubs.rsc.org
The unique properties of nanomaterials, in particular gold nanoparticles (GNPs) have
applications for a wide range of biomedical applications. GNPs have been proposed as …

Gold nanoparticle imaging and radiotherapy of brain tumors in mice

JF Hainfeld, HM Smilowitz, MJ O 'Connor… - …, 2013 - Taylor & Francis
Aim: To test intravenously injected gold nanoparticles for x-ray imaging and radiotherapy
enhancement of large, imminently lethal, intracerebral malignant gliomas. Materials & …

Catalytic activity imperative for nanoparticle dose enhancement in photon and proton therapy

LRH Gerken, A Gogos, FHL Starsich, H David… - Nature …, 2022 - nature.com
Nanoparticle-based radioenhancement is a promising strategy for extending the therapeutic
ratio of radiotherapy. While (pre) clinical results are encouraging, sound mechanistic …

The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy

L Sancey, F Lux, S Kotb, S Roux… - The British journal of …, 2014 - academic.oup.com
A new efficient type of gadolinium-based theranostic agent (AGuIX®) has recently been
developed for MRI-guided radiotherapy (RT). These new particles consist of a polysiloxane …

[HTML][HTML] Enhancement of radiosensitization by metal-based nanoparticles in cancer radiation therapy

XY Su, PD Liu, H Wu, N Gu - Cancer biology & medicine, 2014 - ncbi.nlm.nih.gov
Radiation therapy performs an important function in cancer treatment. However, resistance
of tumor cells to radiation therapy still remains a serious concern, so the study of …