[HTML][HTML] G-protein signaling: back to the future
CR McCudden, MD Hains, RJ Kimple… - Cellular and molecular …, 2005 - Springer
Heterotrimeric G-proteins are intracellular partners of G-protein-coupled receptors (GPCRs).
GPCRs act on inactive Gα· GDP/Gβγ heterotrimers to promote GDP release and GTP …
GPCRs act on inactive Gα· GDP/Gβγ heterotrimers to promote GDP release and GTP …
Nonhuman primate optogenetics: recent advances and future directions
Optogenetics is the use of genetically coded, light-gated ion channels or pumps (opsins) for
millisecond resolution control of neural activity. By targeting opsin expression to specific cell …
millisecond resolution control of neural activity. By targeting opsin expression to specific cell …
[HTML][HTML] Perrault syndrome is caused by recessive mutations in CLPP, encoding a mitochondrial ATP-dependent chambered protease
Perrault syndrome is a genetically and clinically heterogeneous autosomal-recessive
condition characterized by sensorineural hearing loss and ovarian failure. By a combination …
condition characterized by sensorineural hearing loss and ovarian failure. By a combination …
Return of the GDI: the GoLoco motif in cell division
FS Willard, RJ Kimple… - Annual review of …, 2004 - annualreviews.org
▪ Abstract The GoLoco motif is a 19-amino-acid sequence with guanine nucleotide
dissociation inhibitor activity against G-alpha subunits of the adenylyl-cyclase-inhibitory …
dissociation inhibitor activity against G-alpha subunits of the adenylyl-cyclase-inhibitory …
Accessory proteins for G proteins: partners in signaling
M Sato, JB Blumer, V Simon… - Annu. Rev. Pharmacol …, 2006 - annualreviews.org
▪ Abstract Accessory proteins involved in signal processing through heterotrimeric G proteins
are generally defined as proteins distinct from G protein–coupled receptor (GPCR), G …
are generally defined as proteins distinct from G protein–coupled receptor (GPCR), G …
[HTML][HTML] RORα coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways
DA Gold, SH Baek, NJ Schork, DW Rose, DLD Larsen… - Neuron, 2003 - cell.com
The cerebellum provides an excellent system for understanding how afferent and target
neurons coordinate sequential intercellular signals and cell-autonomous genetic programs …
neurons coordinate sequential intercellular signals and cell-autonomous genetic programs …
[HTML][HTML] Membrane interactions of G proteins and other related proteins
O Vögler, JM Barceló, C Ribas, PV Escribá - Biochimica et Biophysica Acta …, 2008 - Elsevier
Guanine nucleotide-binding proteins, G proteins, propagate incoming messages from
receptors to effector proteins. They switch from an inactive to active state by exchanging a …
receptors to effector proteins. They switch from an inactive to active state by exchanging a …
[HTML][HTML] Maturation of human pluripotent stem cell-derived cerebellar neurons in the absence of co-culture
The cerebellum plays a critical role in all vertebrates, and many neurological disorders are
associated with cerebellum dysfunction. A major limitation in cerebellar research has been …
associated with cerebellum dysfunction. A major limitation in cerebellar research has been …
[HTML][HTML] Minimal Purkinje cell-specific PCP2/L7 promoter virally available for rodents and non-human primates
Cell-type-specific promoters in combination with viral vectors and gene-editing technology
permit efficient gene manipulation in specific cell populations. Cerebellar Purkinje cells play …
permit efficient gene manipulation in specific cell populations. Cerebellar Purkinje cells play …
[HTML][HTML] Platinum black/gold nanoparticles/polyaniline modified electrochemical microneedle sensors for continuous in vivo monitoring of pH value
T Ming, T Lan, M Yu, H Wang, J Deng, D Kong, S Yang… - Polymers, 2023 - mdpi.com
Continuous in vivo monitoring (CIVM) of pH value is essential for personalized medicine, as
many diseases are closely related to acid–base imbalances. However, conventional pH …
many diseases are closely related to acid–base imbalances. However, conventional pH …