A growing body of literature reports on the upregulation of CXC motif chemokine receptor 4
(CXCR4) in a variety of cancer entities, rendering this receptor as suitable target for …

Opinion statement Neuroendocrine neoplasms (NEN) are a heterogeneous group of
tumours derived from cells of neuroendocrine origin and can potentially arise everywhere in …

In recent years, molecular imaging addressing the CXC motif chemokine receptor 4
(CXCR4) has increasingly been used in various clinical settings. Here, we aimed to assess …

Purpose To elucidate the influence of CXC motif chemokine receptor 4 (CXCR4)–directed
imaging on staging and proposed oncologic management in patients with digestive system …

CXC-motif chemokine receptor 4 (CXCR4) is a novel predictive biomarker for metastasis
and poor prognosis in individuals with malignancies. CXCL12 is the only cognate ligand of …

Background CXC motif chemokine receptor 4 (CXCR4) is overexpressed in various solid
cancers and can be targeted by CXCR4-directed molecular imaging. We aimed to …

Neuroendocrine neoplasms (NEN) are rare and heterogeneous tumors, originating mostly
from the gastro-entero-pancreatic (GEP) tract followed by the lungs. Multidisciplinary …

Chemokine receptors are important components of cellular signaling and play a critical role
in directing leukocytes during inflammatory reactions. Their importance extends to numerous …

Background CXCR4-directed positron emission tomography/computed tomography
(PET/CT) has been used as a diagnostic tool in patients with solid tumors. We aimed to …

Cancer stem cells (CSCs) represent both a key driving force and therapeutic target of
tumoral carcinogenesis, tumor evolution, progression, and recurrence. CSC-guided tumor …