Photoaging of the skin
M Ichihashi, H Ando, M Yoshida, Y Niki… - Anti-Aging Medicine, 2009 - jstage.jst.go.jp
Extrinsic skin aging is superimposed on intrinsic skin aging process and is due primarily to
UVR (solar ultraviolet radiation) and partly by other factors, such as infrared light, smoking …
UVR (solar ultraviolet radiation) and partly by other factors, such as infrared light, smoking …
Cyclooxygenase-dependent signaling is causally linked to non-melanoma skin carcinogenesis: pharmacological, genetic, and clinical evidence
K Müller-Decker - Cancer and Metastasis Reviews, 2011 - Springer
Abstract Cyclooxygenase (COX)-derived prostaglandins (PGs) exhibit manifold functions in
acute and chronic skin inflammation induced by a number of physical (ultraviolet (UV) light …
acute and chronic skin inflammation induced by a number of physical (ultraviolet (UV) light …
[HTML][HTML] Epidermal COX-2 induction following ultraviolet irradiation: suggested mechanism for the role of COX-2 inhibition in photoprotection
CS Tripp, EAG Blomme, KS Chinn, MM Hardy… - Journal of Investigative …, 2003 - Elsevier
The cyclooxygenase isoforms, COX-1 and COX-2, are involved in the biosynthesis of
prostaglandin E 2, a major prostaglandin involved in epidermal homeostasis and repair …
prostaglandin E 2, a major prostaglandin involved in epidermal homeostasis and repair …
Prostaglandin E2–prostoglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression
K Soontrapa, T Honda, D Sakata… - Proceedings of the …, 2011 - National Acad Sciences
UV radiation induces systemic immunosuppression. Because nonsteroidal anti-inflammatory
drugs suppress UV-induced immunosuppression, prostanoids have been suspected as a …
drugs suppress UV-induced immunosuppression, prostanoids have been suspected as a …
Topical application of a selective cyclooxygenase inhibitor suppresses UVB mediated cutaneous inflammation
TA Wilgus, MS Ross, ML Parrett… - Prostaglandins & other lipid …, 2000 - Elsevier
Ultraviolet B (UVB) radiation causes much of the cutaneous damage after both acute and
long-term exposure, and is also the most important etiologic agent in human skin cancer …
long-term exposure, and is also the most important etiologic agent in human skin cancer …
Prostaglandin E2 is required for ultraviolet B-induced skin inflammation via EP2 and EP4 receptors
K Kabashima, M Nagamachi, T Honda… - Laboratory …, 2007 - nature.com
Keratinocytes are the major target of sunlight, and they produce prostaglandin (PG) E 2
upon ultraviolet (UV) exposure. Although indomethacin, one of cyclooxygenase inhibitors, is …
upon ultraviolet (UV) exposure. Although indomethacin, one of cyclooxygenase inhibitors, is …
[HTML][HTML] CXCL1 inhibition regulates UVB-induced skin inflammation and tumorigenesis in Xpa-deficient mice
M Kunisada, C Hosaka, C Takemori, E Nakano… - Journal of Investigative …, 2017 - Elsevier
Xeroderma pigmentosum complementation group A is a hereditary disease characterized by
early onset of skin cancers and freckle-like pigmented maculae in sun-exposed sites …
early onset of skin cancers and freckle-like pigmented maculae in sun-exposed sites …
Involvement of EGF receptor activation in the induction of cyclooxygenase‐2 in HaCaT keratinocytes after UVB
M Ashida, T Bito, A Budiyanto… - Experimental …, 2003 - Wiley Online Library
Because selective inhibition of cyclooxygenase‐2 (COX‐2) suppressed the induction of skin
tumors in mice by UV and as UV has been shown to induce expression of COX‐2 in skin …
tumors in mice by UV and as UV has been shown to induce expression of COX‐2 in skin …
Prostaglandin E2 Promotes UV radiation-induced immune suppression through DNA hypermethylation
R Prasad, SK Katiyar - Neoplasia, 2013 - Elsevier
Exposure of mice to UV radiation results in suppression of the contact hypersensitivity (CHS)
response. Here, we report that the UV-induced suppression of CHS is associated with …
response. Here, we report that the UV-induced suppression of CHS is associated with …
The time-dependent expressions of IL-1β, COX-2, MCP-1 mRNA in skin wounds of rabbits
R Bai, L Wan, M Shi - Forensic science international, 2008 - Elsevier
In this study, we investigated the time-dependent expression of IL-1β, COX-2, MCP-1 mRNA
after incised wounds in rabbit skin using real-time fluorescent quantitative PCR. The tested …
after incised wounds in rabbit skin using real-time fluorescent quantitative PCR. The tested …