Autophagy and apoptosis cascade: which is more prominent in neuronal death?
Autophagy and apoptosis are two crucial self-destructive processes that maintain cellular
homeostasis, which are characterized by their morphology and regulated through signal …
homeostasis, which are characterized by their morphology and regulated through signal …
Apoptotic cell death regulation in neurons
E Hollville, SE Romero, M Deshmukh - The FEBS journal, 2019 - Wiley Online Library
Apoptosis plays a major role in shaping the developing nervous system during
embryogenesis as neuronal precursors differentiate to become post‐mitotic neurons …
embryogenesis as neuronal precursors differentiate to become post‐mitotic neurons …
Targeting the core of neurodegeneration: FoxO, mTOR, and SIRT1
K Maiese - Neural regeneration research, 2021 - journals.lww.com
The global increase in lifespan noted not only in developed nations, but also in large
developing countries parallels an observed increase in a significant number of non …
developing countries parallels an observed increase in a significant number of non …
Apoptosis, autophagy, necrosis and their multi galore crosstalk in neurodegeneration
S Saleem - Neuroscience, 2021 - Elsevier
The progression of neurodegenerative disorders is mainly characterized by immense
neuron loss and death of glial cells. The mechanisms which are active and regulate …
neuron loss and death of glial cells. The mechanisms which are active and regulate …
Cellular metabolism: A fundamental component of degeneration in the nervous system
K Maiese - Biomolecules, 2023 - mdpi.com
It is estimated that, at minimum, 500 million individuals suffer from cellular metabolic
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is …
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is …
Cognitive impairment and dementia: gaining insight through circadian clock gene pathways
K Maiese - Biomolecules, 2021 - mdpi.com
Neurodegenerative disorders affect fifteen percent of the world's population and pose a
significant financial burden to all nations. Cognitive impairment is the seventh leading cause …
significant financial burden to all nations. Cognitive impairment is the seventh leading cause …
[HTML][HTML] Neurodegeneration, memory loss, and dementia: the impact of biological clocks and circadian rhythm
K Maiese - Frontiers in bioscience (Landmark edition), 2021 - ncbi.nlm.nih.gov
Methods and results: Novel work with biological clock genes that oversee circadian rhythm
may meet this critical need by focusing upon the pathways of the mechanistic target of …
may meet this critical need by focusing upon the pathways of the mechanistic target of …
[HTML][HTML] Nicotinamide as a foundation for treating neurodegenerative disease and metabolic disorders
K Maiese - Current neurovascular research, 2021 - ncbi.nlm.nih.gov
Neurodegenerative disorders impact more than one billion individuals worldwide and are
intimately tied to metabolic disease that can affect another nine hundred individuals …
intimately tied to metabolic disease that can affect another nine hundred individuals …
Cognitive impairment in multiple sclerosis
K Maiese - Bioengineering, 2023 - mdpi.com
Almost three million individuals suffer from multiple sclerosis (MS) throughout the world, a
demyelinating disease in the nervous system with increased prevalence over the last five …
demyelinating disease in the nervous system with increased prevalence over the last five …
The metabolic basis for nervous system dysfunction in alzheimer's disease, parkinson's disease, and huntington's disease
K Maiese - Current neurovascular research, 2023 - benthamdirect.com
Disorders of metabolism affect multiple systems throughout the body but may have the
greatest impact on both central and peripheral nervous systems. Currently available …
greatest impact on both central and peripheral nervous systems. Currently available …