The percutaneous device dilemma describes etiological factors, centered around the
disrupted epithelial tissue surrounding non-remodelable devices, that contribute to rampant …

Simple Summary Integrins play key roles in mediating cell adhesion and delivering chemical
and mechanical signals to the interior of the cell. Consequently, they actively control cellular …

Recognition of laminin by integrin receptors is central to the epithelial cell adhesion to
basement membrane, but the structural background of this molecular interaction remained …

Anchored cells of the basal epidermis constantly undergo proliferation in an overcrowded
environment. An important regulator of epidermal proliferation is YAP, which can be …

Intestinal stem cells are non-quiescent, dividing epithelial cells that rapidly differentiate into
progenitor cells of the absorptive and secretory cell lineages. The kinetics of this process is …

Extracellular matrix (ECM) proteins fill the space between cells in multicellular organisms,
contributing to the structure of organs and tissues. The mechanical properties of ECM are …

Breast cancer is the most common malignancy affecting women worldwide. Importantly,
there have been significant improvements in prevention, early diagnosis, and treatment …

The phenotypes of each breast cancer subtype are defined by their transcriptomes.
However, the transcription factors that regulate differential patterns of gene expression that …

Brain dysfunction in myotonic dystrophy type 1 (DM1), the prototype of toxic RNA disorders,
has been mainly attributed to neuronal RNA misprocessing, while little attention has been …

This study sets the stage for the therapeutic use of Ac 5 ManNTProp, an N-
acetylmannosamine (ManNAc) analog that installs thiol-modified sialoglycans onto the …