Transparent neural interfaces: challenges and solutions of microengineered multimodal implants designed to measure intact neuronal populations using high …

Z Fekete, A Zátonyi, A Kaszás, M Madarász… - Microsystems & …, 2023 - nature.com
The aim of this review is to present a comprehensive overview of the feasibility of using
transparent neural interfaces in multimodal in vivo experiments on the central nervous …

Targeted optical neural stimulation: a new era for personalized medicine

A Ping, L Pan, J Zhang, K Xu, KE Schriver… - The …, 2023 - journals.sagepub.com
Targeted optical neural stimulation comprises infrared neural stimulation and optogenetics,
which affect the nervous system through induced thermal transients and activation of light …

[HTML][HTML] Infrared neural stimulation in human cerebral cortex

L Pan, A Ping, KE Schriver, AW Roe, J Zhu, K Xu - Brain Stimulation, 2023 - Elsevier
Background Modulation of brain circuits by electrical stimulation has led to exciting and
powerful therapies for diseases such as Parkinson's. Because human brain organization is …

Fabrication and in vivo 2-photon microscopy validation of transparent PEDOT: PSS microelectrode arrays

G Dijk, A Kaszas, J Pas, RP O'Connor - Microsystems & …, 2022 - nature.com
Transparent microelectrode arrays enable simultaneous electrical recording and optical
imaging of neuronal networks in the brain. Electrodes made of the conducting polymer poly …

Bidirectional modulation of evoked synaptic transmission by pulsed infrared light

X Zhu, JW Lin, MY Sander - Scientific Reports, 2022 - nature.com
Abstract Infrared (IR) neuromodulation (INM) has been demonstrated as a novel modulation
modality of neuronal excitability. However, the effects of pulsed IR light on synaptic …

Histological and electrophysiological evidence on the safe operation of a sharp-tip multimodal optrode during infrared neuromodulation of the rat cortex

ÁC Horváth, S Borbély, F Mihók, P Fürjes, P Barthó… - Scientific Reports, 2022 - nature.com
Infrared neuromodulation is an emerging technology in neuroscience that exploits the
inherent thermal sensitivity of neurons to excite or inhibit cellular activity. Since there is …

Behavioral, neural and ultrastructural alterations in a graded-dose 6-OHDA mouse model of early-stage Parkinson's disease

A Slézia, P Hegedüs, E Rusina, K Lengyel, N Solari… - Scientific Reports, 2023 - nature.com
Studying animal models furthers our understanding of Parkinson's disease (PD)
pathophysiology by providing tools to investigate detailed molecular, cellular and circuit …

[HTML][HTML] Emerging trends in the development of flexible optrode arrays for electrophysiology

RM Almasri, F Ladouceur, D Mawad… - APL …, 2023 - pubs.aip.org
Optical-electrode (optrode) arrays use light to modulate excitable biological tissues and/or
transduce bioelectrical signals into the optical domain. Light offers several advantages over …

Model-based correction of rapid thermal confounds in fluorescence neuroimaging of targeted perturbation

N Davoudi, H Estrada, A Özbek, S Shoham… - …, 2024 - spiedigitallibrary.org
Significance An array of techniques for targeted neuromodulation is emerging, with high
potential in brain research and therapy. Calcium imaging or other forms of functional …

Advantages, Pitfalls, and Developments of All Optical Interrogation Strategies of Microcircuits in vivo

S Papaioannou, P Medini - Frontiers in neuroscience, 2022 - frontiersin.org
The holy grail for every neurophysiologist is to conclude a causal relationship between an
elementary behaviour and the function of a specific brain area or circuit. Our effort to map …