Reactive oxygen species (ROS) are generated as by-products of normal cellular metabolic
activities. Superoxide dismutase, glutathione peroxidase, and catalase are the enzymes …

Gastric cancer is a major source of global cancer mortality with limited treatment options and
poor patient survival. As our molecular understanding of gastric cancer improves, we are …

Chronic infection with Helicobacter pylori cagA-positive strains is the strongest risk factor for
gastric cancer. The cagA gene product, CagA, is delivered into gastric epithelial cells via the …

Although most H. pylori infectors are asymptomatic, some may develop serious disease,
such as gastric adenocarcinoma, gastric high-grade B cell lymphoma and peptic ulcer …

Nitric oxide (NO), is a ubiquitous, water soluble, free radical gas, which plays key role in
various physiological as well as pathological processes. Over past decades, NO has …

Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

Invasive gastric carcinoma is preceded by a cascade of precancerous lesions. The first
recognized histologic change is active chronic inflammation, which may persist as such: non …

The Japan Gastroenterological Endoscopy Society developed the Guideline for Endoscopic
Diagnosis of Early Gastric Cancer based on scientific methods. Endoscopy for the diagnosis …

Helicobacter pylori (H. pylori) is one of the most important human pathogens, infecting
approximately half of the global population. Despite its high prevalence, only a subset of H …

Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …