The role of microRNAs, long non-coding RNAs, and circular RNAs in cervical cancer

ML Tornesello, R Faraonio, L Buonaguro… - Frontiers in …, 2020 - frontiersin.org
Prolonged infection of uterine cervix epithelium with human papillomavirus (HPV) and
constitutive expression of viral oncogenes have been recognized as the main cause of the …

Clinical implications of (epi) genetic changes in HPV-induced cervical precancerous lesions

RDM Steenbergen, PJF Snijders… - Nature Reviews …, 2014 - nature.com
Infection of cervical epithelium with high-risk human papilloma virus (hrHPV) might result in
productive or transforming cervical intraepithelial neoplasia (CIN) lesions, the morphology of …

High-risk human papillomaviral oncogenes E6 and E7 target key cellular pathways to achieve oncogenesis

NSL Yeo-Teh, Y Ito, S Jha - International journal of molecular sciences, 2018 - mdpi.com
Infection with high-risk human papillomavirus (HPV) has been linked to several human
cancers, the most prominent of which is cervical cancer. The integration of the viral genome …

The interplay between viral-derived miRNAs and host immunity during infection

R Mishra, A Kumar, H Ingle, H Kumar - Frontiers in immunology, 2020 - frontiersin.org
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene
expression during cellular processes. The host-encoded miRNAs are known to modulate the …

Pathogenesis of human papillomavirus‐associated mucosal disease

IJ Groves, N Coleman - The Journal of pathology, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) are a necessary cause of carcinoma of the cervix and other
mucosal epithelia. Key events in high‐risk HPV (HRHPV)‐associated neoplastic …

[HTML][HTML] Human papillomaviruses in epigenetic regulations

J Durzynska, K Lesniewicz, E Poreba - Mutation Research/Reviews in …, 2017 - Elsevier
Abstract Human Papillomaviruses (HPVs) are double-stranded DNA viruses, that infect
epithelial cells and are etiologically involved in the development of human cancer. Today …

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

SZ Bahojb Mahdavi, A Jebelli… - Medicinal Research …, 2024 - Wiley Online Library
Infections caused by viruses as the smallest infectious agents, pose a major threat to global
public health. Viral infections utilize different host mechanisms to facilitate their own …

[HTML][HTML] Referateband: HPV–A different view on Head and Neck Cancer

C Wittekindt, S Wagner, SJ Sharma… - Laryngo-rhino …, 2018 - ncbi.nlm.nih.gov
Head and neck cancer is the sixth most common cancer with over 500000 annually reported
incident cases worldwide. Besides major risk factors tobacco and alcohol, oropharyngeal …

HPV-driven oncogenesis—much more than the E6 and E7 oncoproteins

J Janiszewska, M Kostrzewska-Poczekaj… - Journal of Applied …, 2024 - Springer
High-risk human papillomaviruses are well-established drivers of several cancer types
including cervical, head and neck, penile as well as anal cancers. While the E6 and E7 viral …

NQO1 overexpression is associated with poor prognosis in squamous cell carcinoma of the uterine cervix

Y Ma, J Kong, G Yan, X Ren, D Jin, T Jin, L Lin, Z Lin - BMC cancer, 2014 - Springer
Abstract Background NQO1 (NAD (P) H: quinone oxidoreductase-1), located on
chromosome 16q22, functions primarily to protect normal cells from oxidant stress and …