Mass spectrometry approaches to glycomic and glycoproteomic analyses

LR Ruhaak, G Xu, Q Li, E Goonatilleke… - Chemical …, 2018 - ACS Publications
Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides
(glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate …

Current trends in quantitative proteomics–an update

H Li, J Han, J Pan, T Liu, CE Parker… - Journal of Mass …, 2017 - Wiley Online Library
Proteins can provide insights into biological processes at the functional level, so they are
very promising biomarker candidates. The quantification of proteins in biological samples …

Ultra-large chemical libraries for the discovery of high-affinity peptide binders

AJ Quartararo, ZP Gates, BA Somsen… - Nature …, 2020 - nature.com
High-diversity genetically-encoded combinatorial libraries (108− 1013 members) are a rich
source of peptide-based binding molecules, identified by affinity selection. Synthetic libraries …

A novel and highly sensitive sandwich-type immunosensor for prostate-specific antigen detection based on MWCNTs-Fe3O4 nanocomposite

A Shamsazar, A Asadi, D Seifzadeh… - Sensors and Actuators B …, 2021 - Elsevier
Due to the importance of early diagnosis of prostate cancer, an ultrasensitive
electrochemical immunosensor was developed to detect prostate-specific antigen (PSA) …

Enhanced electrochemical and SERS signals by self-assembled gold microelectrode arrays: A dual readout platform for multiplex immumoassay of tumor biomarkers

X Gu, K Wang, J Qiu, Y Wang, S Tian, Z He… - Sensors and Actuators B …, 2021 - Elsevier
In this study, a dual readout biosensor is reported that combines electrochemical and
surface-enhanced Raman scattering (SERS) for a multiplexed immunoassay of tumor …

Recent advances in the mass spectrometry methods for glycomics and cancer

MJ Kailemia, G Xu, M Wong, Q Li… - Analytical …, 2017 - pmc.ncbi.nlm.nih.gov
The review focuses on recent aspects (last three years) of glycosylation analyses that
provide relevant information about cancer. It includes recent development in glycan and …

Smart sampling as the “Spot‐on” Method for LC‐MS protein analysis from dried blood spots

C Johannsen, A Mrsa, TG Halvorsen… - Journal of Separation …, 2023 - Wiley Online Library
This perspective explores the feasibility of smart sampling with dried blood spots for the
determination of proteins and peptides from human biomatrices using liquid …

Pushing the detection limits: Strategies towards highly sensitive optical-based protein detection

N Momenbeitollahi, T Cloet, H Li - Analytical and Bioanalytical Chemistry, 2021 - Springer
Proteins are one of the main constituents of living cells. Studying the quantities of proteins
under physiological and pathological conditions can give valuable insights into health …

Recent advances on protein-based quantification of extracellular vesicles

T Cloet, N Momenbeitollahi, H Li - Analytical Biochemistry, 2021 - Elsevier
Extracellular vesicles (EVs) are secreted by almost all cells into the circulatory system and
have the important function of intercellular communication. Ranging in size from 50 to 1000 …

Mass tag-based mass spectrometric immunoassay and its bioanalysis applications

M Liu, D Miao, S Qin, H Liu, Y Bai - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
The sensitive and accurate determination of macromolecular biomarkers is in high demand
for clinical diagnosis. Mass spectrometric immunoassay (MSIA) combines the advantages of …