Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021 - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …

Thyroid dysfunction and diabetes mellitus: two closely associated disorders

B Biondi, GJ Kahaly, RP Robertson - Endocrine reviews, 2019 - academic.oup.com
Thyroid dysfunction and diabetes mellitus are closely linked. Several studies have
documented the increased prevalence of thyroid disorders in patients with diabetes mellitus …

Nanoparticle‐enhanced radiotherapy to trigger robust cancer immunotherapy

Q Chen, J Chen, Z Yang, J Xu, L Xu, C Liang… - Advanced …, 2019 - Wiley Online Library
External radiotherapy is extensively used in clinic to destruct tumors by locally applied
ionizing‐radiation beams. However, the efficacy of radiotherapy is usually limited by tumor …

Endocrine toxicity of cancer immunotherapy targeting immune checkpoints

LS Chang, R Barroso-Sousa, SM Tolaney… - Endocrine …, 2019 - academic.oup.com
Immune checkpoints are small molecules expressed by immune cells that play critical roles
in maintaining immune homeostasis. Targeting the immune checkpoints cytotoxic T …

Inhibitors of immune checkpoints—PD-1, PD-L1, CTLA-4—new opportunities for cancer patients and a new challenge for internists and general practitioners

MZ Wojtukiewicz, MM Rek, K Karpowicz… - Cancer and Metastasis …, 2021 - Springer
The treatment of cancer patients with immune checkpoint inhibitors (ICI)(anti-CTLA-4, anti-
PD-1, anti-PD-L1, combined therapy anti-PD-1/PD-L1 with anti-CTLA-4) has without doubt …

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

Q Chen, L Xu, C Liang, C Wang, R Peng… - Nature communications, 2016 - nature.com
A therapeutic strategy that can eliminate primary tumours, inhibit metastases, and prevent
tumour relapses is developed herein by combining adjuvant nanoparticle-based …

Immunotherapy in the treatment of metastatic melanoma: current knowledge and future directions

M Ralli, A Botticelli, IC Visconti… - Journal of …, 2020 - Wiley Online Library
Melanoma is one of the most immunologic malignancies based on its higher prevalence in
immune‐compromised patients, the evidence of brisk lymphocytic infiltrates in both primary …

Platelet PD-L1 reflects collective intratumoral PD-L1 expression and predicts immunotherapy response in non-small cell lung cancer

C Hinterleitner, J Strähle, E Malenke… - Nature …, 2021 - nature.com
Immune-checkpoint inhibitors (ICI) have transformed oncological therapy. Up to 20% of all
non-small cell lung cancers (NSCLCs) show durable responses upon treatment with ICI …

Autoimmune polyendocrine syndromes

ES Husebye - The Rose and Mackay Textbook of Autoimmune …, 2024 - Elsevier
Autoimmune polyendocrinopathies are traditionally divided into two distinct syndromes,
autoimmune polyendocrine syndrome type 1 and 2 (APS-1 and-2). The first is a monogenic …

[HTML][HTML] Immune-related adverse events with immune checkpoint blockade: a comprehensive review

JM Michot, C Bigenwald, S Champiat, M Collins… - European journal of …, 2016 - Elsevier
Cancer immunotherapy is coming of age; it has prompted a paradigm shift in oncology, in
which therapeutic agents are used to target immune cells rather than cancer cells. The first …