3 biological activity of polyene antibiotics

SM Hammond - Progress in medicinal chemistry, 1977 - Elsevier
Publisher Summary This chapter discusses polyenes in clinical use and those polyenes with
properties that contribute to the understanding of the mechanism of action of the group as a …

[图书][B] Male reproductive function and semen: themes and trends in physiology, biochemistry and investigative andrology

T Mann, C Lutwak-Mann - 2012 - books.google.com
To present a coherent and meaningful survey of scientific research endeavour in an area
that has expanded as fast as physiology and biochemistry of reproduction in the male is no …

[HTML][HTML] Action of ionophore A23187 at the cellular level. Separation of effects at the plasma and mitochondrial membranes.

DF Babcock, NL First, HA Lardy - Journal of Biological Chemistry, 1976 - Elsevier
Bovine epididymal spermatozoa incubated aerobically in vitro in the presence of 0.1 to 0.2
mM CaCl2 accumulate 25 to 50 nmol of calcium/10 (8) cells. The addition of low …

Changes in calcium transport in mammalian sperm mitochondria and plasma membrane irradiated at 633 nm (HeNe laser)

H Breitbart, T Levinshal, N Cohen, H Friedmann… - … of Photochemistry and …, 1996 - Elsevier
The effect of light on calcium transport in mammalian sperm mitrochondria and plasma
membrane was studied. Digitonine-treated spermatozoa and plasma membrane vesicles …

The interaction of polyene antibiotics with thin lipid membranes

TE Andreoli, M Monahan - The Journal of general physiology, 1968 - rupress.org
Optically black, thin lipid membranes prepared from sheep erythrocyte lipids have a high dc
resistance (Rm≅ 108 ohm-cm2) when the bathing solutions contain NaCl or KCl. The ionic …

Alteration of membrane permeability to calcium ions during maturation of bovine spermatozoa

DF Babcock, JP Singh, HA Lardy - Developmental biology, 1979 - Elsevier
Bovine spermatozoa, maturing in the caudal epididymis, apparently have a low content of
mobilizable Ca 2+(6±1 nmoles Ca 2+ 10 8 cells) in situ, but will accumulate added Ca 2+ …

Mechanism of bilirubin toxicity on tissue culture cells: factors that affect toxicity, reversibility by albumin, and comparison with other respiratory poisons and surfactants

ML Cowger - Biochemical Medicine, 1971 - Elsevier
Various factors that influence the cytotoxic effects of bilirubin, a known electron-transport
poison, on mammalian cells in culture have been studied. The cellular uptake of free …

Energy conservation capacity and morphological integrity of mitochondria in hypotonically treated rabbit epididymal spermatozoa

E Keyhani, BT Storey - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1973 - Elsevier
Hypotonic treatment of rabbit epididymal spermatozoa in 10 mM phosphate buffer disrupts
the plasma membrane and removes the cytoplasmic droplet from those cells to which it is …

[HTML][HTML] Mitochondrial metabolism of pyruvate in bovine spermatozoa.

SM Hutson, C Van Dop, HA Lardy - Journal of Biological Chemistry, 1977 - Elsevier
Treatment with the polyene antibiotic, filipin, renders the spermatozoan cell membrane
permeable to small molecules, but not to the intracellular enzymes aldolase and lactate …

[HTML][HTML] Transport mechanism for succinate and phosphate localized in the plasma membrane of bovine spermatozoa

DF Babcock, NL First, HA Lardy - Journal of Biological Chemistry, 1975 - Elsevier
Bovine spermatozoa accumulated a small amount of 32Pi during aerobic incubation in vitro.
At least 50% of the acquired isotope rapidly entered cellular nucleotides. Both adenosine …