After the recognition of the essential role of the immune system in the progression of type 2
diabetes mellitus, more studies are focused on the effects produced by the abnormal …

Although a critical role of adaptive immune system has been confirmed in driving local and
systemic inflammation in type 2 diabetes and promoting insulin resistance, the underlying …

Atherosclerosis (ATS), the change in structure and function of arteries with associated lesion
formation and altered blood flow, is the leading cause of cardiovascular disease, the number …

Background Chronic immune activation has been described in the development of
cardiovascular diseases (CVDs) and in the pathogenesis of type 2 diabetes mellitus (T2D) …

Chronic inflammation and hyperglycaemia are well-established aspects in the pathogenesis
of type 2 diabetes mellitus (T2D), including the progression of its associated complications …

Background: Type 2 diabetes (T2D) is a low-grade inflammatory condition with
abnormalities in the immune response mediated by T lymphocytes and macrophages. Drug …

Studies indicated that imbalance of proinflammatory and anti-inflammatory cytokines may
contribute to development of type 2 diabetes mellitus (T2DM). We hypothesized that …

Hyperglycemia, a hallmark of diabetes and various metabolic disorders, has profound
implications for immune cell function. The relationship between elevated blood glucose …

Fundamento: alrededor del cinco porciento de los pacientes con la COVID-19 tienen una
evolución crítica, con insuficiencia respiratoria, de los cuales aproximadamente la mitad …

Introduction Type 2 diabetes (T2D) is a common chronic heterogeneous metabolic disorder.
However, the roles of pyroptosis and infiltrating immune cells in islet dysfunction of patients …