[HTML][HTML] Stem cell-based regenerative medicine
N Rajabzadeh, E Fathi, R Farahzadi - Stem cell investigation, 2019 - ncbi.nlm.nih.gov
Recent developments in the stem cell biology provided new hopes in treatment of diseases
and disorders that yet cannot be treated. Stem cells have the potential to differentiate into …
and disorders that yet cannot be treated. Stem cells have the potential to differentiate into …
Microglia: biology and pathology
MB Graeber, WJ Streit - Acta neuropathologica, 2010 - Springer
The past 20 years have seen a gain in knowledge on microglia biology and microglia
functions in disease that exceeds the expectations formulated when the microglia “immune …
functions in disease that exceeds the expectations formulated when the microglia “immune …
Intracerebroventricular injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer's disease dementia: a phase I clinical trial
Backgrounds Alzheimer's disease is the most common cause of dementia, and currently,
there is no disease-modifying treatment. Favorable functional outcomes and reduction of …
there is no disease-modifying treatment. Favorable functional outcomes and reduction of …
Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes
T Katsuda, R Tsuchiya, N Kosaka, Y Yoshioka… - Scientific reports, 2013 - nature.com
Alzheimer's disease (AD) is characterized by the accumulation of β-amyloid peptide (Aβ) in
the brain because of an imbalance between Aβ production and clearance. Neprilysin (NEP) …
the brain because of an imbalance between Aβ production and clearance. Neprilysin (NEP) …
Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β …
MA de Godoy, LM Saraiva, LRP de Carvalho… - Journal of Biological …, 2018 - ASBMB
Alzheimer's disease (AD) is a disabling and highly prevalent neurodegenerative condition,
for which there are no effective therapies. Soluble oligomers of the amyloid-β peptide (AβOs) …
for which there are no effective therapies. Soluble oligomers of the amyloid-β peptide (AβOs) …
Treatment of Alzheimer's disease: beyond symptomatic therapies
FR Buccellato, M D'Anca, GM Tartaglia… - International Journal of …, 2023 - mdpi.com
In an ever-increasing aged world, Alzheimer's disease (AD) represents the first cause of
dementia and one of the first chronic diseases in elderly people. With 55 million people …
dementia and one of the first chronic diseases in elderly people. With 55 million people …
Functional role of mesenchymal stem cells in the treatment of chronic neurodegenerative diseases
D Lo Furno, G Mannino… - Journal of cellular …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) can differentiate into not only cells of mesodermal
lineages, but also into endodermal and ectodermal derived elements, including neurons …
lineages, but also into endodermal and ectodermal derived elements, including neurons …
Human umbilical cord blood-derived mesenchymal stem cells improve neuropathology and cognitive impairment in an Alzheimer's disease mouse model through …
HJ Lee, JK Lee, H Lee, JE Carter, JW Chang, W Oh… - Neurobiology of …, 2012 - Elsevier
Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSC) have a potential
therapeutic role in the treatment of neurological disorders, but their current clinical usage …
therapeutic role in the treatment of neurological disorders, but their current clinical usage …
Intracerebral transplantation of bone marrow-derived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in Alzheimer's disease …
JK Lee, HK Jin, S Endo, EH Schuchman, JE Carter… - Stem …, 2010 - academic.oup.com
Alzheimer's disease (AD) is characterized by the deposition of amyloid-β peptide (Aβ) and
the formation of neurofibrillary tangles. Transplantation of bone marrow-derived …
the formation of neurofibrillary tangles. Transplantation of bone marrow-derived …
Extracellular vesicles derived from human Wharton's jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced …
V Bodart-Santos, LRP de Carvalho… - Stem cell research & …, 2019 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have been explored as promising
tools for treatment of several neurological and neurodegenerative diseases. MSCs release …
tools for treatment of several neurological and neurodegenerative diseases. MSCs release …