[HTML][HTML] Microbiota in health and diseases

K Hou, ZX Wu, XY Chen, JQ Wang, D Zhang… - Signal transduction and …, 2022 - nature.com
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?

CA Akdis - Nature Reviews Immunology, 2021 - nature.com
There has been a steep increase in allergic and autoimmune diseases, reaching epidemic
proportions and now affecting more than one billion people worldwide. These diseases are …

Dual role of indoles derived from intestinal microbiota on human health

X Ye, H Li, K Anjum, X Zhong, S Miao, G Zheng… - Frontiers in …, 2022 - frontiersin.org
Endogenous indole and its derivatives (indoles), considered as promising N-substituted
heterocyclic compounds, are tryptophan metabolites derived from intestinal microbiota and …

Chronic kidney disease

P Romagnani, G Remuzzi, R Glassock… - Nature reviews Disease …, 2017 - nature.com
Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural
abnormalities or impaired excretory renal function suggestive of a loss of functional …

Resveratrol modulates the gut microbiota and inflammation to protect against diabetic nephropathy in mice

TT Cai, XL Ye, RR Li, H Chen, YY Wang… - Frontiers in …, 2020 - frontiersin.org
Oral administration of resveratrol is able to ameliorate the progression of diabetic
nephropathy (DN); however, its mechanisms of action remain unclear. Recent evidence …

Gut microbiota and hypertension: association, mechanisms and treatment

Z Yang, Q Wang, Y Liu, L Wang, Z Ge, Z Li… - Clinical and …, 2023 - Taylor & Francis
Objectives Hypertension is one of the most important risk factors for cardio-cerebral vascular
diseases, which brings a heavy economic burden to society and becomes a major public …

Inflammation in renal diseases: new and old players

V Andrade-Oliveira, O Foresto-Neto… - Frontiers in …, 2019 - frontiersin.org
Inflammation, a process intimately linked to renal disease, can be defined as a complex
network of interactions between renal parenchymal cells and resident immune cells, such as …

Intestinal microbiome and fitness in kidney disease

B Meijers, P Evenepoel, HJ Anders - Nature reviews nephrology, 2019 - nature.com
Environmental changes can induce diversity shifts within ecosystems that affect interactions
between species. Similarly, the development of kidney disease induces shifts within the …

Alkaline phosphatase: a novel treatment target for cardiovascular disease in CKD

M Haarhaus, V Brandenburg… - Nature Reviews …, 2017 - nature.com
Cardiovascular disease is the main cause of early death in the settings of chronic kidney
disease (CKD), type 2 diabetes mellitus (T2DM), and ageing. Cardiovascular events can be …

Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients

KY Xu, GH Xia, JQ Lu, MX Chen, X Zhen, S Wang… - Scientific Reports, 2017 - nature.com
Chronic kidney disease (CKD) patients have an increased risk of cardiovascular diseases
(CVDs). The present study aimed to investigate the gut microbiota and blood trimethylamine …