Endolysin, a promising solution against antimicrobial resistance
Antimicrobial resistance (AMR) is a global crisis for human public health which threatens the
effective prevention and control of ever-increasing infectious diseases. The advent of …
effective prevention and control of ever-increasing infectious diseases. The advent of …
Endolysins as emerging alternative therapeutic agents to counter drug-resistant infections
Endolysins are the lytic products of bacteriophages which play a specific role in the release
of phage progeny by degrading the peptidoglycan of the host bacterium. In the light of …
of phage progeny by degrading the peptidoglycan of the host bacterium. In the light of …
Gram-negative bacterial lysins
C Ghose, CW Euler - Antibiotics, 2020 - mdpi.com
Antibiotics have had a profound impact on human society by enabling the eradication of
otherwise deadly infections. Unfortunately, antibiotic use and overuse has led to the rapid …
otherwise deadly infections. Unfortunately, antibiotic use and overuse has led to the rapid …
Phage lysins for fighting bacterial respiratory infections: a new generation of antimicrobials
Lower respiratory tract infections and tuberculosis are responsible for the death of about 4.5
million people each year and are the main causes of mortality in children under 5 years of …
million people each year and are the main causes of mortality in children under 5 years of …
[HTML][HTML] Bacteriophage-encoded enzymes destroying bacterial cell membranes and walls, and their potential use as antimicrobial agents
Ł Grabowski, K Łepek, M Stasiłojć… - Microbiological …, 2021 - Elsevier
Appearance of pathogenic bacteria resistant to most, if not all, known antibiotics is currently
one of the most significant medical problems. Therefore, development of novel antibacterial …
one of the most significant medical problems. Therefore, development of novel antibacterial …
Bacteriophage-derived endolysins to target gram-negative bacteria
Bacteriophage-encoded endolysins (lysins) have emerged as a novel class of antibacterial
agents to combat the surging antibiotic resistance. Lysins have specific structures and …
agents to combat the surging antibiotic resistance. Lysins have specific structures and …
Potential of bacteriophage proteins as recognition molecules for pathogen detection
SP Costa, CL Nogueira, AP Cunha… - Critical Reviews in …, 2023 - Taylor & Francis
Bacterial pathogens are leading causes of infections with high mortality worldwide having a
great impact on healthcare systems and the food industry. Gold standard methods for …
great impact on healthcare systems and the food industry. Gold standard methods for …
Catalytic diversity and cell wall binding repeats in the phage‐encoded endolysins
SS Broendum, AM Buckle… - Molecular …, 2018 - Wiley Online Library
Bacteriophage‐encoded endolysins can recognize and bind specific bacteria, and act to
cleave the glycosidic and/or amide bonds in the peptidoglycan (PG) bacterial cell wall …
cleave the glycosidic and/or amide bonds in the peptidoglycan (PG) bacterial cell wall …
What's in a Name? An overview of the proliferating nomenclature in the field of phage lysins
In the last few years, the volume of research produced on phage lysins has grown
spectacularly due to the interest in using them as alternative antimicrobials. As a result, a …
spectacularly due to the interest in using them as alternative antimicrobials. As a result, a …
Antibacterial synergy between a phage endolysin and citric acid against the Gram-negative kiwifruit pathogen Pseudomonas syringae pv. actinidiae
Horticultural diseases caused by bacterial pathogens provide an obstacle to crop production
globally. Management of the infection of kiwifruit by the Gram-negative phytopathogen …
globally. Management of the infection of kiwifruit by the Gram-negative phytopathogen …