The actin cytoskeleton as an active adaptive material

S Banerjee, ML Gardel… - Annual review of …, 2020 - annualreviews.org
Actin is the main protein used by biological cells to adapt their structure and mechanics to
their needs. Cellular adaptation is made possible by molecular processes that strongly …

Architecture shapes contractility in actomyosin networks

GH Koenderink, EK Paluch - Current opinion in cell biology, 2018 - Elsevier
Myosin-driven contraction of the actin cytoskeleton is at the base of cell and tissue
morphogenesis. At the molecular level, myosin motors drive contraction by sliding actin …

The 2020 motile active matter roadmap

G Gompper, RG Winkler, T Speck… - Journal of Physics …, 2020 - iopscience.iop.org
Activity and autonomous motion are fundamental in living and engineering systems. This
has stimulated the new field of'active matter'in recent years, which focuses on the physical …

Phase intensity nanoscope (PINE) opens long-time investigation windows of living matter

G Cui, Y Liu, D Zu, X Zhao, Z Zhang, DY Kim… - Nature …, 2023 - nature.com
Fundamental to all living organisms and living soft matter are emergent processes in which
the reorganization of individual constituents at the nanoscale drives group-level movements …

[HTML][HTML] The physics of active polymers and filaments

RG Winkler, G Gompper - The journal of chemical physics, 2020 - pubs.aip.org
Active matter agents consume internal energy or extract energy from the environment for
locomotion and force generation. Already, rather generic models, such as ensembles of …

F-actin architecture determines constraints on myosin thick filament motion

CG Muresan, ZG Sun, V Yadav, AP Tabatabai… - Nature …, 2022 - nature.com
Active stresses are generated and transmitted throughout diverse F-actin architectures
within the cell cytoskeleton, and drive essential behaviors of the cell, from cell division to …

Mechanical stimulation of single cells by reversible host-guest interactions in 3D microscaffolds

M Hippler, K Weißenbruch, K Richler, ED Lemma… - Science …, 2020 - science.org
Many essential cellular processes are regulated by mechanical properties of their
microenvironment. Here, we introduce stimuli-responsive composite scaffolds fabricated by …

Controlling organization and forces in active matter through optically defined boundaries

TD Ross, HJ Lee, Z Qu, RA Banks, R Phillips… - Nature, 2019 - nature.com
Living systems are capable of locomotion, reconfiguration and replication. To perform these
tasks, cells spatiotemporally coordinate the interactions of force-generating,'active'molecules …

Principles of actomyosin regulation in vivo

P Agarwal, R Zaidel-Bar - Trends in Cell Biology, 2019 - cell.com
The actomyosin cytoskeleton is responsible for most force-driven processes in cells and
tissues. How it assembles into the necessary structures at the right time and place is an …

Sculpting with stem cells: how models of embryo development take shape

JV Veenvliet, PF Lenne, DA Turner, I Nachman… - …, 2021 - journals.biologists.com
During embryogenesis, organisms acquire their shape given boundary conditions that
impose geometrical, mechanical and biochemical constraints. A detailed integrative …