Abstract Reactome (http://www. reactome. org) is a collaboration among groups at the
Ontario Institute for Cancer Research, Cold Spring Harbor Laboratory, New York University …

Reactome describes biological pathways as chemical reactions that closely mirror the actual
physical interactions that occur in the cell. Recent extensions of our data model …

G-protein coupled receptors (GPCRs) are popular biological targets for drug discovery and
development. To date there are more than 140 orphan GPCRs, ie, receptors whose …

The majority of hormones stimulates and mediates their signal transduction via G protein-
coupled receptors (GPCRs). The signal is transmitted into the cell due to the association of …

G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic
of receptor structure. Substantial experimental evidence supports the existence of GPCR …

Abstract Reactome (http://www. reactome. org) is an open‐source, expert‐authored, peer‐
reviewed, manually curated database of reactions, pathways and biological processes. We …

G protein-coupled receptors (GPCRs) are the largest family of membrane proteins and play
a critical role as pharmacological targets. An improved understanding of GPCRs' …

G protein-coupled receptors (GPCRs), a superfamily of cell-surface receptors involved in
virtually all physiological processes, are the major target class for approved drugs. Imaging …

Background In marine organisms, and in particular for benthic invertebrates including
echinoderms, olfaction is a dominant sense with chemosensation being a critical signalling …

Colon cancer is one of the most common cancer types. Its positive correlation with general
obesity has led to increasing amounts of research focusing on the role of adipokines in …