As a type of elastomeric polymers, non-degradable polyurethanes (PUs) have a long history
of being used in clinics, whereas biodegradable PUs have been developed in recent …

Biomaterials of either natural or synthetic origin are used to fabricate implantable devices, as
carriers for bioactive molecules or as substrates to facilitate tissue regeneration. For the …

Corneal damage forms scar tissue and manifests as permanent corneal opacity, which is the
main cause of visual impairment caused by corneal diseases. To treat these diseases …

Regeneration of corneal stroma has always been a challenge due to its sophisticated
structure and keratocyte-fibroblast transformation. In this study, we fabricate grid poly (ε …

The cornea and the skin are both organs that provide the outer barrier of the body. Both
tissues have developed intrinsic mechanisms that protect the organism from a wide range of …

Conventional allograft therapy for corneal scarring is widespread and successful, but donor
tissue is not universally available, and some grafts fail owing to rejection and complications …

Corneal transplantation is an important surgical treatment for many common corneal
diseases. However, a worldwide shortage of tissue from suitable corneal donors has meant …

The cornea is a tough transparent tissue admitting and focusing light in the eye. More than
90% of the cornea is stroma, a highly organized, transparent connective tissue maintained …

A severe shortage of good quality donor cornea is now an international crisis in public
health. Alternatives for donor tissue need to be urgently developed to meet the increasing …

Background: Since the cornea is responsible for transmitting and focusing light into the eye,
injury or pathology affecting any layer of the cornea can cause a detrimental effect on visual …