Neoadjuvant chemotherapy in pancreatic cancer: an appraisal of the current high-level evidence

PC Müller, MC Frey, CM Ruzza, F Nickel, C Jost… - Pharmacology, 2021 - karger.com
At the time of diagnosis, only about 20% of patients with pancreatic ductal adenocarcinoma
(PDAC) have resectable disease. PDAC treatment necessitates a multidisciplinary …

Surgical resection rates after neoadjuvant therapy for localized pancreatic ductal adenocarcinoma: meta-analysis

ZJ Brown, V Heh, HE Labiner, GN Brock… - British Journal of …, 2023 - academic.oup.com
Background Neoadjuvant therapy is increasingly being used before surgery for localized
pancreatic cancer. Given the importance of completing multimodal therapy, the aim of this …

NCCN guidelines insights: pancreatic adenocarcinoma, version 1.2019: featured updates to the NCCN guidelines

MA Tempero, MP Malafa, EG Chiorean, B Czito… - Journal of the National …, 2019 - jnccn.org
The NCCN Guidelines for Pancreatic Adenocarcinoma discuss the diagnosis and
management of adenocarcinomas of the exocrine pancreas and are intended to assist with …

Defining and predicting early recurrence in 957 patients with resected pancreatic ductal adenocarcinoma

VP Groot, G Gemenetzis, AB Blair… - Annals of …, 2019 - journals.lww.com
Objectives: To establish an evidence-based cut-off to differentiate between early and late
recurrence and to compare clinicopathologic risk factors between the two groups. Summary …

Potentially curable pancreatic cancer: American Society of Clinical Oncology clinical practice guideline

AA Khorana, PB Mangu, J Berlin… - Journal of Clinical …, 2016 - ascopubs.org
Purpose To provide evidence-based recommendations to oncologists and others on
potentially curative therapy for patients with localized pancreatic cancer. Methods ASCO …

Pancreatogastrostomy versus pancreatojejunostomy for RECOnstruction after PANCreatoduodenectomy (RECOPANC, DRKS 00000767): perioperative and long …

T Keck, UF Wellner, M Bahra, F Klein, O Sick… - 2016 - journals.lww.com
Objectives: To assess pancreatic fistula rate and secondary endpoints after
pancreatogastrostomy (PG) versus pancreatojejunostomy (PJ) for reconstruction in …

Safety and efficacy of preoperative or postoperative chemotherapy for resectable pancreatic adenocarcinoma (PACT-15): a randomised, open-label, phase 2–3 trial

M Reni, G Balzano, S Zanon, A Zerbi… - The lancet …, 2018 - thelancet.com
Background Pancreatic ductal adenocarcinoma are known to metastasise early and a
rationale exists for the investigation of preoperative chemotherapy in patients with …

Completion of adjuvant chemotherapy after upfront surgical resection for pancreatic cancer is uncommon yet associated with improved survival

AM Altman, K Wirth, S Marmor, E Lou, K Chang… - Annals of surgical …, 2019 - Springer
Background Multiple trials have demonstrated a survival benefit for adjuvant chemotherapy
after resection of pancreatic adenocarcinoma. This study aimed to identify the rate for …

[HTML][HTML] The risk of not receiving adjuvant chemotherapy after resection of pancreatic ductal adenocarcinoma: a nationwide analysis

TM Mackay, FJ Smits, D Roos, BA Bonsing, K Bosscha… - Hpb, 2020 - Elsevier
Background The relation between type of postoperative complication and not receiving
chemotherapy after resection of pancreatic ductal adenocarcinoma (PDAC) is unclear. The …

Assessment of textbook oncologic outcomes following pancreaticoduodenectomy for pancreatic adenocarcinoma

PJ Sweigert, E Eguia, MS Baker… - Journal of surgical …, 2020 - Wiley Online Library
Background Composite outcomes may more accurately reflect patient and provider
expectations around optimal care. We sought to determine the impact of achieving a so …