Recent advances in supramolecular analytical chemistry using optical sensing

L You, D Zha, EV Anslyn - Chemical reviews, 2015 - ACS Publications
The field of supramolecular chemistry has been flourishing since J.-M. Lehn, DJ Cram, and
CJ Pedersen were awarded the 1987 Nobel Prize in Chemistry. By Prof. Lehn's definition, 1 …

Chirality sensing using stereodynamic probes with distinct electronic circular dichroism output

C Wolf, KW Bentley - Chemical Society Reviews, 2013 - pubs.rsc.org
Circular dichroism (CD) spectroscopy is one of the most useful techniques for the
stereochemical analysis of chiral biopolymers and fine chemicals. It has become invaluable …

Optical analysis of reaction yield and enantiomeric excess: a new paradigm ready for prime time

BT Herrera, SL Pilicer, EV Anslyn… - Journal of the …, 2018 - ACS Publications
This Perspective highlights the advances of optical methods for asymmetric reaction
discovery. Optical analysis allows for the determination of absolute configuration …

Circular dichroism sensing: Strategies and applications

JSSK Formen, JR Howard, EV Anslyn… - Angewandte Chemie …, 2024 - Wiley Online Library
The analysis of the absolute configuration, enantiomeric composition, and concentration of
chiral compounds are frequently encountered tasks across the chemical and health …

Rapid optical methods for enantiomeric excess analysis: From enantioselective indicator displacement assays to exciton-coupled circular dichroism

HH Jo, CY Lin, EV Anslyn - Accounts of Chemical Research, 2014 - ACS Publications
Conspectus The advent of high-throughput screening (HTS) for chiral catalysts has
encouraged the development of fast methods for determining enantiomeric excess (ee) …

Molecular Recognition and Chirality Sensing of Epoxides in Water Using Endo-Functionalized Molecular Tubes

LL Wang, Z Chen, WE Liu, H Ke… - Journal of the …, 2017 - ACS Publications
Chiral epoxides are important intermediates in chemistry and biology. The high-throughput
screening of asymmetric epoxidation conditions requires fast determination of the absolute …

A Self‐Assembled Cage for Wide‐Scope Chiral Recognition in Water

G Wu, Y Chen, S Fang, L Tong, L Shen… - Angewandte Chemie …, 2021 - Wiley Online Library
Herein, we report the self‐assembly of an anionic homochiral octahedral cage by
condensing six Ga3+ cations and four trisacylhydrazone ligands. The robust nature of the …

Chirality sensing of amines, diamines, amino acids, amino alcohols, and α-hydroxy acids with a single probe

KW Bentley, YG Nam, JM Murphy… - Journal of the American …, 2013 - ACS Publications
A stereodynamic probe for determination of the absolute configuration and enantiomeric
composition of chiral amines, diamines, amino alcohols, amino acids, and α-hydroxy …

Stereodynamic chemosensor with selective circular dichroism and fluorescence readout for in situ determination of absolute configuration, enantiomeric excess, and …

KW Bentley, C Wolf - Journal of the American Chemical Society, 2013 - ACS Publications
A stereodynamic chemosensor having a parallel arrangement of a substrate-binding
salicylaldehyde unit and an adjacent pyridyl N-oxide fluorophore undergoes rapid …

Biomimetic chirality sensing with pyridoxal-5′-phosphate

SL Pilicer, PR Bakhshi, KW Bentley… - Journal of the American …, 2017 - ACS Publications
Pyridoxal-5′-phosphate (PLP) is introduced to a biomimetic indicator displacement assay
for simultaneous determination of the absolute configuration, enantiomeric composition and …