Tutorial: a computational framework for the design and optimization of peripheral neural interfaces

S Romeni, G Valle, A Mazzoni, S Micera - Nature Protocols, 2020 - nature.com
Peripheral neural interfaces have been successfully used in the recent past to restore
sensory-motor functions in disabled subjects and for the neuromodulation of the autonomic …

Peripherally induced reconditioning of the central nervous system: a proposed mechanistic theory for sustained relief of chronic pain with percutaneous peripheral …

TR Deer, S Eldabe, SM Falowski… - Journal of Pain …, 2021 - Taylor & Francis
Peripheral nerve stimulation (PNS) is an effective tool for the treatment of chronic pain,
although its efficacy and utilization have previously been significantly limited by technology …

[HTML][HTML] Modeling the excitation of nerve axons under transcutaneous stimulation

N RaviChandran, J Hope, K Aw, A McDaid - Computers in Biology and …, 2023 - Elsevier
Computational models enable a safe and convenient way to study the excitation of nerve
fibers under external stimulation. Contemporary models calculate the electric field …

Anatomical and technical factors affecting the neural response to epidural spinal cord stimulation

HJ Zander, RD Graham, CJ Anaya… - Journal of neural …, 2020 - iopscience.iop.org
Objective. Spinal cord stimulation (SCS) is a common neurostimulation therapy to treat
chronic pain. Computational models represent a valuable tool to study the potential …

A systematic review of computational models for the design of spinal cord stimulation therapies: from neural circuits to patient‐specific simulations

L Liang, A Damiani, M Del Brocco… - The Journal of …, 2023 - Wiley Online Library
Seventy years ago, Hodgkin and Huxley published the first mathematical model to describe
action potential generation, laying the foundation for modern computational neuroscience …

Preferential activation of proprioceptive and cutaneous sensory fibers compared to motor fibers during cervical transcutaneous spinal cord stimulation: a …

RM de Freitas, M Capogrosso, T Nomura… - Journal of Neural …, 2022 - iopscience.iop.org
Objective. Cervical transcutaneous spinal cord stimulation (tSCS) is a promising technology
that can support motor function recovery of upper-limbs after spinal cord injury. Its efficacy …

Dorsal root ganglion stimulation for chronic pain modulates Aβ-fiber activity but not C-fiber activity: A computational modeling study

RD Graham, TM Bruns, B Duan, SF Lempka - Clinical Neurophysiology, 2019 - Elsevier
Objective The goal of this project was to use computational models to investigate which
types of primary sensory neurons are modulated by dorsal root ganglion stimulation (DRGS) …

Automatic calibration of electrode arrays for dexterous neuroprostheses: a review

N RaviChandran, K Aw, A McDaid - Biomedical Physics & …, 2023 - iopscience.iop.org
Background. Electrode arrays can simplify the modulation of shape, size, and position for
customized stimulation delivery. However, the intricacy in achieving the desired outcome …

Computational modelling of nerve stimulation and recording with peripheral visceral neural interfaces

CD Eiber, SC Payne, NP Biscola… - Journal of neural …, 2021 - iopscience.iop.org
Objective. Neuromodulation of visceral nerves is being intensively studied for treating a wide
range of conditions, but effective translation requires increasing the efficacy and …

Evoked potentials recorded from the spinal cord during neurostimulation for pain: a computational modeling study

CJ Anaya, HJ Zander, RD Graham… - … : Technology at the …, 2020 - Elsevier
Objectives Spinal cord stimulation (SCS) for pain is typically implemented in an open-loop
manner using parameters that remain largely unchanged. To improve the overall efficacy …