[HTML][HTML] Progress in the application of sustained-release drug microspheres in tissue engineering

L Ruan, M Su, X Qin, Q Ruan, W Lang, M Wu, Y Chen… - Materials Today Bio, 2022 - Elsevier
Sustained-release drug-loaded microspheres provide a long-acting sustained release, with
targeted and other effects. There are many types of sustained-release drug microspheres …

Extracellular matrix molecules and their potential contribution to the function of transplanted pancreatic islets

LA Llacua, MM Faas, P de Vos - Diabetologia, 2018 - Springer
Extracellular matrix (ECM) molecules are responsible for structural and biochemical support,
as well as for regulation of molecular signalling and tissue repair in many organ structures …

[HTML][HTML] Type 1 diabetes and engineering enhanced islet transplantation

A Jeyagaran, C Lu, A Zbinden, AL Birkenfeld… - Advanced drug delivery …, 2022 - Elsevier
The development of new therapeutic approaches to treat type 1 diabetes mellitus (T1D)
relies on the precise understanding and deciphering of insulin-secreting β-cell biology, as …

What is the biological and clinical relevance of fibrin?

RI Litvinov, JW Weisel - Seminars in thrombosis and …, 2016 - thieme-connect.com
As our knowledge of the structure and functions of fibrinogen and fibrin has increased
tremendously, several key findings have given some people a superficial impression that the …

Angiogenic abnormalities in diabetes mellitus: mechanistic and clinical aspects

GP Fadini, M Albiero, BM Bonora… - The Journal of Clinical …, 2019 - academic.oup.com
Context Diabetes causes severe pathological changes to the microvasculature in many
organs and tissues and is at the same time associated with an increased risk of coronary …

Synthetic hydrogels mimicking basement membrane matrices to promote cell-matrix interactions

R Cruz-Acuna, AJ García - Matrix Biology, 2017 - Elsevier
Naturally-derived materials have been extensively used as 3D cellular matrices as their
inherent bioactivity makes them suitable for the study of many cellular processes …

Injectable biomaterials for dental tissue regeneration

HJ Haugen, P Basu, M Sukul, JF Mano… - International journal of …, 2020 - mdpi.com
Injectable biomaterials scaffolds play a pivotal role for dental tissue regeneration, as such
materials are highly applicable in the dental field, particularly when compared to pre-formed …

Progress of 3D bioprinting in organ manufacturing

D Song, Y Xu, S Liu, L Wen, X Wang - Polymers, 2021 - mdpi.com
Three-dimensional (3D) bioprinting is a family of rapid prototyping technologies, which
assemble biomaterials, including cells and bioactive agents, under the control of a computer …

Biodegradable and non-biodegradable biomaterials and their effect on cell differentiation

R Geevarghese, SS Sajjadi, A Hudecki… - International Journal of …, 2022 - mdpi.com
Biomaterials for tissue scaffolds are key components in modern tissue engineering and
regenerative medicine. Targeted reconstructive therapies require a proper choice of …

Oxygenation strategies for encapsulated islet and beta cell transplants

KK Papas, H De Leon, TM Suszynski… - Advanced drug delivery …, 2019 - Elsevier
Human allogeneic islet transplantation (ITx) is emerging as a promising treatment option for
qualified patients with type 1 diabetes. However, widespread clinical application of …