Characterization of connective tissues using near-infrared spectroscopy and imaging

IO Afara, R Shaikh, E Nippolainen, W Querido… - Nature …, 2021 - nature.com
Near-infrared (NIR) spectroscopy is a powerful analytical method for rapid, non-destructive
and label-free assessment of biological materials. Compared to mid-infrared spectroscopy …

[HTML][HTML] Applications of vibrational spectroscopy for analysis of connective tissues

W Querido, S Kandel, N Pleshko - Molecules, 2021 - mdpi.com
Advances in vibrational spectroscopy have propelled new insights into the molecular
composition and structure of biological tissues. In this review, we discuss common …

[HTML][HTML] Spatial analysis of the osteoarthritis microenvironment: techniques, insights, and applications

X Fan, AR Sun, RSE Young, IO Afara, BR Hamilton… - Bone Research, 2024 - nature.com
Osteoarthritis (OA) is a debilitating degenerative disease affecting multiple joint tissues,
including cartilage, bone, synovium, and adipose tissues. OA presents diverse clinical …

Injectable hydrogels for articular cartilage and nucleus pulposus repair: status quo and prospects

B Zoetebier, TC Schmitz, K Ito, M Karperien… - … Engineering Part A, 2022 - liebertpub.com
Osteoarthritis (OA) and chronic low back pain due to degenerative (intervertebral) disc
disease (DDD) are two of the major causes of disabilities worldwide, affecting hundreds of …

[HTML][HTML] An automated deep learning pipeline based on advanced optimisations for leveraging spectral classification modelling

D Passos, P Mishra - Chemometrics and Intelligent Laboratory Systems, 2021 - Elsevier
In deep learning (DL) modelling for spectral data, a major challenge is related to the choice
of DL network architecture and the selection of the best hyperparameters. Often, slight …

[HTML][HTML] Visible and near-infrared spectroscopy enables differentiation of normal and early osteoarthritic human knee joint articular cartilage

A Linus, P Tanska, JK Sarin, E Nippolainen… - Annals of Biomedical …, 2023 - Springer
Osteoarthritis degenerates cartilage and impairs joint function. Early intervention
opportunities are missed as current diagnostic methods are insensitive to early tissue …

[HTML][HTML] Sports Analytics and Text Mining NBA Data to Assess Recovery from Injuries and Their Economic Impact

V Sarlis, G Papageorgiou, C Tjortjis - Computers, 2023 - mdpi.com
Injuries are an unfortunate part of professional sports. This study aims to explore the multi-
dimensional impact of injuries in professional basketball, focusing on player performance …

[HTML][HTML] Optical imaging of dynamic collagen processes in health and disease

LE Iannucci, CS Dranoff, MA David… - Frontiers in Mechanical …, 2022 - frontiersin.org
Collagen is a major structural component of nearly every tissue in the human body, whose
hierarchical organization imparts specific mechanical properties and defines overall tissue …

[HTML][HTML] Non-invasive detection and differentiation of apoptotic and necroptotic cell death in vitro

J Li, X Zhao, B Wu, Z Ji, H Liu, X Wang, H Zhang… - … of Photochemistry and …, 2023 - Elsevier
Cell death plays an important role in the development of multicellular organisms and the
maintenance of adult homeostasis. However, traditional methods of cell death detection can …

Unsupervised Learning in NBA Injury Recovery: Advanced Data Mining to Decode Recovery Durations and Economic Impacts

G Papageorgiou, V Sarlis, C Tjortjis - Information, 2024 - mdpi.com
This study utilized advanced data mining and machine learning to examine player injuries in
the National Basketball Association (NBA) from 2000–01 to 2022–23. By analyzing a …