Maternal and paternal obesity and type 2 diabetes are recognized risk factors for the
development of metabolic dysfunction in offspring, even when the offspring follow a healthful …

In the last two decades, evidence from human and animal studies suggests that paternal
obesity around the time of conception can have adverse effects on offspring health through …

Maternal obesity has many implications for offspring health that persist throughout their
lifespan that include obesity and cardiovascular complications. Several different factors …

Context Maternal exercise positively influences pregnancy outcomes and metabolic health
in progeny; however, data regarding the effects of different modes of prenatal exercise on …

Insulin resistance (IR) is largely recognized as a unifying feature that underlies metabolic
dysfunction. Both lifestyle and genetic factors contribute to IR. Work from recent years has …

There is an ever increasing prevalence of maternal obesity worldwide such that in many
populations over half of women enter pregnancy either overweight or obese. This review …

Substantial evidence indicated that maternal malnutrition could increase the susceptibility to
obesity, insulin resistance, and type 2 diabetes in adulthood. It is increasingly apparent that …

Metabolic diseases, including obesity, dyslipidemia, and type 2 diabetes, have become
severe challenges worldwide. The Developmental Origins of Health and Disease (DOHaD) …

Pre-pregnancy obesity is a contributing factor for impairments in offspring metabolic health.
Interventional strategies during pregnancy are a potential approach to alleviate and/or …

Context Recent preclinical data suggest exercise during pregnancy can improve the
metabolic phenotype not only of the mother, but of the developing offspring as well …