In situ characterization techniques of protein corona around nanomaterials

F Fu, D Crespy, K Landfester, S Jiang - Chemical Society Reviews, 2024 - pubs.rsc.org
Nanoparticles (NPs) inevitably interact with proteins upon exposure to biological fluids,
leading to the formation of an adsorption layer known as the “protein corona”. This corona …

Does the surface charge of the nanoparticles drive nanoparticle–cell membrane interactions?

S Balog, MS de Almeida, P Taladriz-Blanco… - Current Opinion in …, 2024 - Elsevier
Highlights•Nanoparticle surface charges are influenced by the protein corona.•NP-cell
interactions are not just governed by surface charge•Nanoparticle surface charge must be …

Green synthesized apigenin conjugated gold nanoparticles inhibit cholangiocarcinoma cell activity and endothelial cell angiogenesis in vitro

N Ngernyuang, M Wongwattanakul, W Charusirisawad… - Heliyon, 2022 - cell.com
Cholangiocarcinoma (CCA) is a rare malignancy of the biliary tract with extremely poor
clinical outcomes due to a lack of effective therapies to improve disease management. The …

Neuroinflammation-related proteins NOD2 and spp1 are abnormally upregulated in amyotrophic lateral sclerosis

N de Luna, Á Carbayo, O Dols-Icardo… - Neurology …, 2022 - AAN Enterprises
Background and Objectives Amyotrophic lateral sclerosis (ALS) is a neurodegenerative
disease of unknown etiology and poorly understood pathophysiology. There is no specific …

Biomolecular Corona of Gold Nanoparticles: The Urgent Need for Strong Roots to Grow Strong Branches

L Boselli, V Castagnola, A Armirotti, F Benfenati… - Small, 2024 - Wiley Online Library
Gold nanoparticles (GNPs) are largely employed in diagnostics/biosensors and are among
the most investigated nanomaterials in biology/medicine. However, few GNP‐based …

Nose-to-Brain Delivery of Biomimetic Nanoparticles for Glioblastoma Targeted Therapy

NN Ferreira, CM Leite, NS Moreno… - … Applied Materials & …, 2024 - ACS Publications
Glioblastoma (GBM) is an extremely aggressive form of brain cancer that remains
challenging to treat, especially owing to the lack of effective targeting and drug delivery …

Chemo–Phototherapeutic Effect of Polyoxometalate-Stabilized Gold Nanostars for Cancer Treatment

JF Ramirez Henao, S Boujday, C Wilhelm… - ACS Applied Nano …, 2024 - ACS Publications
A reduced polyoxometalate (POM) functionalized with bisphosphonate (BP) ligands
possessing antitumoral properties was used to synthesize metallic gold nanostars (AuNSs) …

A Review for Uncovering the “Protein-Nanoparticle Alliance”: Implications of the Protein Corona for Biomedical Applications

B Önal Acet, D Gül, RH Stauber, M Odabaşı, Ö Acet - Nanomaterials, 2024 - mdpi.com
Understanding both the physicochemical and biological interactions of nanoparticles is
mandatory for the biomedical application of nanomaterials. By binding proteins …

Nanomedical research and development in Spain: improving the treatment of diseases from the nanoscale

P Fernández-Gómez… - … in Bioengineering and …, 2023 - frontiersin.org
The new and unique possibilities that nanomaterials offer have greatly impacted
biomedicine, from the treatment and diagnosis of diseases, to the specific and optimized …

Nanomedical research and development in Spain: improving the treatment of diseases from the nanoscale

P Fernández, C Pérez de la Lastra, C Tosat-Bitrian… - 2023 - digital.csic.es
The new and unique possibilities that nanomaterials offer have greatly impacted
biomedicine, from the treatment and diagnosis of diseases, to the specific and optimized …