Although amino acids are critical for all forms of life, only proteogenic amino acids that
humans and animals cannot synthesize de novo and therefore must acquire in their diets …

Aspartate is the common precursor of the essential amino acids lysine, threonine,
methionine and isoleucine in higher plants. In addition, aspartate may also be converted to …

We have examined the biochemical and histological effects of high concentrations of
dopamine (0.05-1.0 micromol) injected into the rat striatum. Twenty-four hours after such …

We have increased the lysine content in the seeds of canola and soybean plants by
circumventing the normal feedback regulation of two enzymes of the biosynthetic pathway …

Human and monogastric animals cannot synthesize 10 out of the 20 amino acids and
therefore need to obtain these from their diet. Among the essential amino acids, lysine and …

The essential amino acids lysine, threonine, methionine and isoleucine are synthesised in
higher plants via a common pathway starting with aspartate. The regulation of the pathway is …

Abstract Rice (Oryza sativa L.), a major staple crop worldwide, has limited levels of the
essential amino acid lysine. We previously produced engineered rice with increased lysine …

As an approach to understand the regulation of methionine (Met) metabolism, Arabidopsis
Met over‐accumulating mutants were isolated based on their resistance to selection by …

Amino acid pathways are important targets for plant metabolic engineering. Since plants
represent the major global food supply, large efforts are devoted to increasing the content of …

Lysine is an essential amino acid for mammals but its concentration in cereals, one of our
main food sources, is low. Research over the past 40 years has unraveled many …