Patients with end-stage renal disease suffer from complex hemostatic disorders. Uremic
patients show a bleeding diathesis that is mainly due to abnormalities of primary …

Patients with end‐stage renal disease (ESRD) develop hemostatic disorders mainly in the
form of bleeding diatheses. Hemorrhage can occur at cutaneous, mucosal, or serosal sites …

Background—Contrast-induced acute kidney injury (CI-AKI), defined as a serum creatinine
increase≥ 0.5 mg/dL or≥ 25% within 72 hours after contrast exposure, is a common …

Chronic kidney disease (CKD) is a growing global health problem. CKD is typically
associated with a prothrombotic tendency in the early stages of the disease, whereas in its …

The uremic syndrome is a complex mixture of organ dysfunctions, which is attributed to the
retention of a myriad of compounds that under normal condition are excreted by the healthy …

Uremic bleeding syndrome is a recognized consequence of renal failure and can result in
clinically significant sequelae. Although the pathophysiology of the condition has yet to be …

Normal hemostasis is initiated by damage of the vessel wall with exposure of subendothelial
structures to flowing blood and results in the formation of a solid hemostatic plug. The first …

Patients with cirrhosis develop complex alterations in primary hemostasis that include both
hypocoagulable and hypercoagulable features. This includes thrombocytopenia, multiple …

The uremic syndrome can be defined as a deterioration of biochemical and physiologic
functions, in parallel with the progression of renal failure, resulting in complex and variable …

The cause of uremic bleeding has been the subject of a major debate in the last 30 years.
The pathogenesis is considered multifactorial (Table 1); however, platelet-platelet and …